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Literature DB >> 27097301

Lysosomal protein relocation as an adaptation mechanism to extracellular acidosis.

Mehdi Damaghi¹, Robert J Gillies¹.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2016 PMID： 27097301 PMCID： PMC5036926 DOI： 10.1080/15384101.2016.1176394

Source DB: PubMed Journal: Cell Cycle ISSN： 1551-4005 Impact factor: 4.534

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7 in total

Review 1. The effects of extracellular pH on immune function.

Authors: A Lardner
Journal: J Leukoc Biol Date: 2001-04 Impact factor: 4.962

2. Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: mechanism of low pH-induced VEGF.

Authors: Lei Xu; Dai Fukumura; Rakesh K Jain
Journal: J Biol Chem Date: 2001-12-11 Impact factor: 5.157

3. Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.

Authors: Shari Pilon-Thomas; Krithika N Kodumudi; Asmaa E El-Kenawi; Shonagh Russell; Amy M Weber; Kimberly Luddy; Mehdi Damaghi; Jonathan W Wojtkowiak; James J Mulé; Arig Ibrahim-Hashim; Robert J Gillies
Journal: Cancer Res Date: 2015-12-30 Impact factor: 12.701

4. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments.

Authors: Jonathan W Wojtkowiak; Jennifer M Rothberg; Virendra Kumar; Karla J Schramm; Edward Haller; Joshua B Proemsey; Mark C Lloyd; Bonnie F Sloane; Robert J Gillies
Journal: Cancer Res Date: 2012-06-19 Impact factor: 12.701

5. Acidity generated by the tumor microenvironment drives local invasion.

Authors: Veronica Estrella; Tingan Chen; Mark Lloyd; Jonathan Wojtkowiak; Heather H Cornnell; Arig Ibrahim-Hashim; Kate Bailey; Yoganand Balagurunathan; Jennifer M Rothberg; Bonnie F Sloane; Joseph Johnson; Robert A Gatenby; Robert J Gillies
Journal: Cancer Res Date: 2013-01-03 Impact factor: 12.701

Review 6. A microenvironmental model of carcinogenesis.

Authors: Robert A Gatenby; Robert J Gillies
Journal: Nat Rev Cancer Date: 2008-01 Impact factor: 60.716

7. Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane.

Authors: Mehdi Damaghi; Narges K Tafreshi; Mark C Lloyd; Robert Sprung; Veronica Estrella; Jonathan W Wojtkowiak; David L Morse; John M Koomen; Marilyn M Bui; Robert A Gatenby; Robert J Gillies
Journal: Nat Commun Date: 2015-12-10 Impact factor: 14.919

7 in total

4 in total

Lysosomal protein relocation as an adaptation mechanism to extracellular acidosis.

Review 1. The effects of extracellular pH on immune function.

2. Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: mechanism of low pH-induced VEGF.

3. Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.

4. Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments.

5. Acidity generated by the tumor microenvironment drives local invasion.

Review 6. A microenvironmental model of carcinogenesis.

7. Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane.

1. Central role of lactate and proton in cancer cell resistance to glucose deprivation and its clinical translation.

Review 2. Cancer heterogeneity and metastasis: life at the edge.

3. Collagen production and niche engineering: A novel strategy for cancer cells to survive acidosis in DCIS and evolve.

4. Transcriptomic Response to Acidosis Reveals Its Contribution to Bone Metastasis in Breast Cancer Cells.