An Updated Review of Methods and Advancements in Microvascular Blood Flow Imaging.

There has been a consistent growth in research involving imaging of microvasculature over the past few decades. By 2008, publications mentioning the microcirculation had grown more than 2000 per annum. Many techniques have been demonstrated for the measurement of the microcirculation ranging from the earliest invasive techniques to the present high-speed, high-resolution noninvasive imaging techniques. Understanding the microvasculature is vital in tackling fundamental research questions as well as to understand the effects of disease progression on the physiological well-being of an individual. We have previously provided a wide-ranging review covering most of the available techniques and their applications. In this review, we discuss the recent advances made and applications in the field of microcirculation imaging.