Literature DB >> 27096315

Getting the Skinny on CD4(+) T Cell Survival in Fatty Livers.

Christopher M Walker1, Stanley M Lemon2.   

Abstract

Non-alcoholic fatty liver disease is associated with hepatocellular carcinoma. In the March 10 issue of Nature, Greten and colleagues report that this metabolic disruption affects tumor surveillance by depleting CD4+ T helper cells through lipotoxic mechanisms associated with NAFLD.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27096315      PMCID： PMC5381269          DOI： 10.1016/j.immuni.2016.04.001

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  8 in total

Review 1.  Nonalcoholic fatty liver disease and hepatocellular carcinoma.

Authors:  Heinz Zoller; Herbert Tilg
Journal:  Metabolism       Date:  2016-01-23       Impact factor: 8.694

Review 2.  Fibrosis in nonalcoholic Fatty liver disease: mechanisms and clinical implications.

Authors:  Paul Angulo; Mariana Verdelho Machado; Anna Mae Diehl
Journal:  Semin Liver Dis       Date:  2015-05-14       Impact factor: 6.115

Review 3.  Immunological landscape and immunotherapy of hepatocellular carcinoma.

Authors:  Jesús Prieto; Ignacio Melero; Bruno Sangro
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2015-10-20       Impact factor: 46.802

Review 4.  Staying local-antigen presentation in the liver.

Authors:  Percy A Knolle
Journal:  Curr Opin Immunol       Date:  2016-03-12       Impact factor: 7.486

Review 5.  Is genotype 3 of the hepatitis C virus the new villain?

Authors:  Nicolas Goossens; Francesco Negro
Journal:  Hepatology       Date:  2014-04-14       Impact factor: 17.425

Review 6.  Cellular immune responses to hepatocellular carcinoma: lessons for immunotherapy.

Authors:  Nathalie Schmidt; Christoph Neumann-Haefelin; Robert Thimme
Journal:  Dig Dis       Date:  2012-10-24       Impact factor: 2.404

Review 7.  Steatosis in the liver.

Authors:  David Q-H Wang; Piero Portincasa; Brent A Neuschwander-Tetri
Journal:  Compr Physiol       Date:  2013-10       Impact factor: 9.090

8.  NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.

Authors:  Chi Ma; Aparna H Kesarwala; Tobias Eggert; José Medina-Echeverz; David E Kleiner; Ping Jin; David F Stroncek; Masaki Terabe; Veena Kapoor; Mei ElGindi; Miaojun Han; Angela M Thornton; Haibo Zhang; Michèle Egger; Ji Luo; Dean W Felsher; Daniel W McVicar; Achim Weber; Mathias Heikenwalder; Tim F Greten
Journal:  Nature       Date:  2016-03-02       Impact factor: 49.962
  8 in total
  1 in total

Review 1.  Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase.

Authors:  Niharika Samala; Sarah A Tersey; Naga Chalasani; Ryan M Anderson; Raghavendra G Mirmira
Journal:  J Diabetes Complications       Date:  2017-07-31       Impact factor: 2.852
  1 in total

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