| Literature DB >> 27096310 |
Eric I Elliott1, Fayyaz S Sutterwala2.
Abstract
Generally, two signals are required to activate the NLRP3 inflammasome. In this issue of Immunity, Hornung and colleagues (2016) describe an alternative inflammasome activation pathway in human monocytes triggering activation of the NLRP3 inflammasome in response to a single stimulus.Entities:
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Year: 2016 PMID: 27096310 DOI: 10.1016/j.immuni.2016.03.015
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745