Literature DB >> 2709315

Physical characterization of the methanol solvate of urapidil.

S A Botha1, M R Caira, J K Guillory, A P Lötter.   

Abstract

The methanol solvate of urapidil was prepared and characterized by means of differential scanning calorimetry, thermogravimetric analysis, infrared spectroscopy, X-ray powder diffraction, intrinsic dissolution rate, and solution calorimetry. The stoichiometry of the urapidil:methanol solvate was found to be 1:1. The crystal and molecular structures were determined from three-dimensional X-ray data. The stability of the solvate under different storage conditions was also determined.

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Year:  1989        PMID: 2709315     DOI: 10.1002/jps.2600780109

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Preparation and physicochemical characterization of 5 niclosamide solvates and 1 hemisolvate.

Authors:  Elsa C van Tonder; Mabatane D Mahlatji; Sarel F Malan; Wilna Liebenberg; Mino R Caira; Mingna Song; Melgardt M de Villiers
Journal:  AAPS PharmSciTech       Date:  2004-02-23       Impact factor: 3.246

  1 in total

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