Literature DB >> 27092369

'No ordinary meeting': Robert McWhirter and the decline of radical mastectomy.

J J Newmark1.   

Abstract

On 7 January 1948, a meeting was held at the Royal Society of Medicine in London. Its purpose was to settle a controversy. Robert McWhirter, an Edinburgh-based radiotherapist, had been invited to defend the scandalous position advocated by Geoffrey Keynes ten years previously: that radical mastectomy offered no survival advantage when compared to simple mastectomy plus local radiotherapy. The negative publicity surrounding the meeting proved overwhelming for Keynes and he abandoned his research. Indeed, the events of the meeting may have been quietly buried were it not for McWhirter who, over the following decade, pursued Keynes' research. He refined his technique, sparing patients the disfiguring and painful radical mastectomy without compromising overall survival. Later, he garnered support from other researchers, which led to a series of papers confirming his original findings. Towards the end of his career, he also made contributions to service organisation and hormone therapy, eventually holding the Presidency of the Faculty of Radiologists. By keeping the controversy alive, McWhirter was instrumental in overturning 60 years of surgical dogma. He remains a pivotal figure in the history of breast cancer.

Entities:  

Keywords:  Geoffrey Keynes; Rober McWhirter; breast cancer; radical mastectomy

Mesh:

Year:  2016        PMID: 27092369     DOI: 10.4997/JRCPE.2016.110

Source DB:  PubMed          Journal:  J R Coll Physicians Edinb        ISSN: 1478-2715


  1 in total

Review 1.  De-Escalating the Management of In Situ and Invasive Breast Cancer.

Authors:  Fernando A Angarita; Robert Brumer; Matthew Castelo; Nestor F Esnaola; Stephen B Edge; Kazuaki Takabe
Journal:  Cancers (Basel)       Date:  2022-09-20       Impact factor: 6.575

  1 in total

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