Literature DB >> 27091303

Structural Characterization of Kadcoccinin A: A Sesquiterpenoid with a Tricyclo[4.4.0.0(3,10)]decane Scaffold from Kadsura coccinea.

Zheng-Xi Hu1,2, Yi-Ming Shi1, Wei-Guang Wang1, Jian-Wei Tang1, Min Zhou1, Xue Du1, Yong-Hui Zhang2, Jian-Xin Pu1, Han-Dong Sun1.   

Abstract

Kadcoccinin A (1), a cage-like sesquiterpenoid possessing a tricyclo[4.4.0.0(3,10)]decane scaffold, and the biosynthetically related kadcoccinin B (2) were isolated from the stems of Kadsura coccinea. Their structures and absolute configurations were determined from extensive spectroscopic analysis and quantum chemical calculations. Additionally, their cytotoxic and antifungal effects were initially evaluated, and a plausible biosynthetic pathway was proposed.

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Year:  2016        PMID: 27091303     DOI: 10.1021/acs.orglett.6b00919

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  Anti-inflammatory butenolide derivatives from the coral-derived fungus Aspergillus terreus and structure revisions of aspernolides D and G, butyrolactone VI and 4',8''-diacetoxy butyrolactone VI.

Authors:  Mengting Liu; Qun Zhou; Jianping Wang; Junjun Liu; Changxing Qi; Yongji Lai; Hucheng Zhu; Yongbo Xue; Zhengxi Hu; Yonghui Zhang
Journal:  RSC Adv       Date:  2018-04-09       Impact factor: 4.036

Review 2.  Natural Products Research in China From 2015 to 2016.

Authors:  Haishan Liu; Guoliang Zhu; Yaqin Fan; Yuqi Du; Mengmeng Lan; Yibo Xu; Weiming Zhu
Journal:  Front Chem       Date:  2018-03-20       Impact factor: 5.221

3.  Two New Compounds from Schisandra propinqua var. propinqua.

Authors:  Miao Liu; Zheng-Xi Hu; Yuan-Qing Luo; Min Zhou; Wei-Guang Wang; Xiao-Nian Li; Xue Du; Jian-Xin Pu; Han-Dong Sun
Journal:  Nat Prod Bioprospect       Date:  2017-05-03

Review 4.  Harvest, After 50 Years of Sowing.

Authors:  Pema-Tenzin Puno
Journal:  Nat Prod Bioprospect       Date:  2018-07-19

5.  Two New AChE Inhibitors Isolated from Li Folk Herb Heilaohu "Kadsura coccinea" Stems.

Authors:  Sheng Zhuo Huang; Lin Ping Duan; Hao Wang; Wen Li Mei; Hao Fu Dai
Journal:  Molecules       Date:  2019-10-08       Impact factor: 4.411

6.  Roots and stems of Kadsura coccinea extract induced developmental toxicity in zebrafish embryos/larvae through apoptosis and oxidative stress.

Authors:  Zhongshang Xia; Erwei Hao; Zhangmei Chen; Mingzhe Zhang; Yanting Wei; Man Wei; Xiaotao Hou; Zhengcai Du; Jiagang Deng
Journal:  Pharm Biol       Date:  2020-12       Impact factor: 3.503

Review 7.  Kadsura coccinea: A rich source of structurally diverse and biologically important compounds.

Authors:  Yu-Pei Yang; Nusrat Hussain; Liu Zhang; Yan-Zhe Jia; Yu-Qing Jian; Bin Li; Muhammad Iqbal Choudhary; Atta-Ur Rahman; Wei Wang
Journal:  Chin Herb Med       Date:  2020-06-26
  7 in total

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