Literature DB >> 27087169

Minimal C-terminal modification boosts peptide self-assembling ability for necroptosis of cancer cells.

Zhaoqianqi Feng1, Huaimin Wang, Xuewen Du, Junfeng Shi, Jie Li, Bing Xu.   

Abstract

Here we reported the first case in which enhancing self-assembling ability boosts anti-cancer efficacy through a simple and minimal modification of the C-terminus of a d-tripeptide. By only a 2% change of the molecular weight, this facile approach increases the inhibitory activity by over an order of magnitude (IC50 from 431 to 23 μM) towards an osteosarcoma cell line.

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Year:  2016        PMID： 27087169      PMCID： PMC4855835          DOI： 10.1039/c6cc02282k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  36 in total

1.  Enzyme promotes the hydrogelation from a hydrophobic small molecule.

Authors:  Jie Gao; Huaimin Wang; Ling Wang; Jingyu Wang; Deling Kong; Zhimou Yang
Journal:  J Am Chem Soc       Date:  2009-08-19       Impact factor: 15.419

2.  Enzyme-instructed molecular self-assembly confers nanofibers and a supramolecular hydrogel of taxol derivative.

Authors:  Yuan Gao; Yi Kuang; Zu-Feng Guo; Zhihong Guo; Isaac J Krauss; Bing Xu
Journal:  J Am Chem Soc       Date:  2009-09-30       Impact factor: 15.419

3.  Engineering complementary hydrophobic interactions to control β-hairpin peptide self-assembly, network branching, and hydrogel properties.

Authors:  Sameer Sathaye; Huixi Zhang; Cem Sonmez; Joel P Schneider; Christopher M MacDermaid; Christopher D Von Bargen; Jeffery G Saven; Darrin J Pochan
Journal:  Biomacromolecules       Date:  2014-10-17       Impact factor: 6.988

Review 4.  Toxic effects of cis-dichlorodiammineplatinum(II) in man.

Authors:  D D Von Hoff; R Schilsky; C M Reichert; R L Reddick; M Rozencweig; R C Young; F M Muggia
Journal:  Cancer Treat Rep       Date:  1979 Sep-Oct

5.  Cancer cell death induced by the intracellular self-assembly of an enzyme-responsive supramolecular gelator.

Authors:  Akiko Tanaka; Yuki Fukuoka; Yuka Morimoto; Takafumi Honjo; Daisuke Koda; Masahiro Goto; Tatsuo Maruyama
Journal:  J Am Chem Soc       Date:  2015-01-05       Impact factor: 15.419

6.  The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro.

Authors:  Kevin Marley; Stuart C Helfand; Wade A Edris; John E Mata; Alix I Gitelman; Jan Medlock; Bernard Séguin
Journal:  BMC Vet Res       Date:  2013-01-18       Impact factor: 2.741

7.  Ferrocenoyl phenylalanine: a new strategy toward supramolecular hydrogels with multistimuli responsive properties.

Authors:  Zhifang Sun; Zhengyuan Li; Yonghui He; Rujuan Shen; Liu Deng; Minghui Yang; Yizeng Liang; Yi Zhang
Journal:  J Am Chem Soc       Date:  2013-08-28       Impact factor: 15.419

8.  Pericellular hydrogel/nanonets inhibit cancer cells.

Authors:  Yi Kuang; Junfeng Shi; Jie Li; Dan Yuan; Kyle A Alberti; Qiaobing Xu; Bing Xu
Journal:  Angew Chem Int Ed Engl       Date:  2014-05-12       Impact factor: 15.336

9.  Amino acid sequence in constitutionally isomeric tetrapeptide amphiphiles dictates architecture of one-dimensional nanostructures.

Authors:  Honggang Cui; Andrew G Cheetham; E Thomas Pashuck; Samuel I Stupp
Journal:  J Am Chem Soc       Date:  2014-08-21       Impact factor: 15.419

10.  A multiphase transitioning peptide hydrogel for suturing ultrasmall vessels.

Authors:  Daniel J Smith; Gabriel A Brat; Scott H Medina; Dedi Tong; Yong Huang; Johanna Grahammer; Georg J Furtmüller; Byoung Chol Oh; Katelyn J Nagy-Smith; Piotr Walczak; Gerald Brandacher; Joel P Schneider
Journal:  Nat Nanotechnol       Date:  2015-11-02       Impact factor: 39.213
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  14 in total

Review 1.  Supramolecular biofunctional materials.

Authors:  Jie Zhou; Jie Li; Xuewen Du; Bing Xu
Journal:  Biomaterials       Date:  2017-03-12       Impact factor: 12.479

2.  Kinetic Analysis of Nanostructures Formed by Enzyme-Instructed Intracellular Assemblies against Cancer Cells.

Authors:  Jie Li; Domenico Bullara; Xuewen Du; Hongjian He; Stavroula Sofou; Ioannis G Kevrekidis; Irving R Epstein; Bing Xu
Journal:  ACS Nano       Date:  2018-03-21       Impact factor: 15.881

Review 3.  Enzyme-Instructed Self-Assembly for Cancer Therapy and Imaging.

Authors:  Beom Jin Kim; Bing Xu
Journal:  Bioconjug Chem       Date:  2020-02-07       Impact factor: 4.774

Review 4.  Bioinspired assembly of small molecules in cell milieu.

Authors:  Huaimin Wang; Zhaoqianqi Feng; Bing Xu
Journal:  Chem Soc Rev       Date:  2017-05-09       Impact factor: 54.564

5.  Enzymatic Self-Assembly Confers Exceptionally Strong Synergism with NF-κB Targeting for Selective Necroptosis of Cancer Cells.

Authors:  Jie Zhou; Xuewen Du; Xiaoyi Chen; Jiaqing Wang; Ning Zhou; Difei Wu; Bing Xu
Journal:  J Am Chem Soc       Date:  2018-02-06       Impact factor: 15.419

6.  Enzymatic self-assembly of an immunoreceptor tyrosine-based inhibitory motif (ITIM).

Authors:  Natsuko Yamagata; Xiaoyi Chen; Jie Zhou; Jie Li; Xuewen Du; Bing Xu
Journal:  Org Biomol Chem       Date:  2017-07-04       Impact factor: 3.876

7.  The ratio of hydrogelator to precursor controls the enzymatic hydrogelation of a branched peptide.

Authors:  Jiaqi Guo; Hongjian He; Beom Jin Kim; Jiaqing Wang; Meihui Yi; Cheng Lin; Bing Xu
Journal:  Soft Matter       Date:  2020-11-18       Impact factor: 3.679

8.  Trypsin-Instructed Self-Assembly on Endoplasmic Reticulum for Selectively Inhibiting Cancer Cells: Dedicated to Professor George M. Whitesides on the occasion of his 80th birthday.

Authors:  Beom Jin Kim; Yu Fang; Hongjian He; Bing Xu
Journal:  Adv Healthc Mater       Date:  2020-04-28       Impact factor: 9.933

9.  In situ generated D-peptidic nanofibrils as multifaceted apoptotic inducers to target cancer cells.

Authors:  Xuewen Du; Jie Zhou; Huainin Wang; Junfeng Shi; Yi Kuang; Wu Zeng; Zhimou Yang; Bing Xu
Journal:  Cell Death Dis       Date:  2017-02-16       Impact factor: 8.469

10.  Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance.

Authors:  Huaimin Wang; Zhaoqianqi Feng; Youzhi Wang; Rong Zhou; Zhimou Yang; Bing Xu
Journal:  J Am Chem Soc       Date:  2016-12-01       Impact factor: 15.419
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