Literature DB >> 27084296

Regulatory T cells in oral squamous cell carcinoma.

Sai Liu1, Dongjuan Liu1, Jing Li1, Dunfang Zhang2, Qianming Chen1.   

Abstract

Regulatory T cells (Tregs) play a critical role in modulating and maintaining immune homeostasis and tolerance. They accumulate in many types of tumors and play a critical role in tumor evasion of immune surveillance. Oral cancer is characterized by an increase in the number of infiltrating Tregs; however, the significance of this increase on the prognosis of oral cancer is controversial. This review focuses on the function of Tregs in oral squamous cell carcinoma and its implications on prognosis. We also discuss potential therapeutic strategies aimed at Tregs modification in oral SCC.
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  FOXP3; Tregs; oral squamous cell carcinoma; tumor immunotherapy

Mesh：

Year:  2016        PMID： 27084296     DOI： 10.1111/jop.12445

Source DB:  PubMed          Journal:  J Oral Pathol Med        ISSN： 0904-2512            Impact factor:   4.253


  9 in total

1.  Differentiated State of Initiating Tumor Cells Is Key to Distinctive Immune Responses Seen in H-RasG12V-Induced Squamous Tumors.

Authors:  Michael A Podolsky; Jacob T Bailey; Andrew J Gunderson; Carrie J Oakes; Kyle Breech; Adam B Glick
Journal:  Cancer Immunol Res       Date:  2017-01-30       Impact factor: 11.151

2.  Mapping trends and hotspots regarding oral carcinoma and macrophages: a bibliometric analysis of global research.

Authors:  Tuan Zhao; Hao Hu; Xuan Chen; Ye Liu; Heng Wang; Xiaomei Li
Journal:  Am J Transl Res       Date:  2022-07-15       Impact factor: 3.940

3.  Sex determining region Y-box 9 induced microtubule formation and epithelial⁃mesenchymal transition in human oral squamous cell carcinoma CAL27 cells.

Authors:  Sheng Huang; Qi-Yuan Zhang; Ai-E He; Hong-Bo Li; Zhi-Xing Zhang
Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi       Date:  2021-02-01

Review 4.  Predictive factors in the treatment of oral squamous cell carcinoma using PD-1/PD-L1 inhibitors.

Authors:  Antian Gao; Xiao Pan; Xudong Yang; Zitong Lin
Journal:  Invest New Drugs       Date:  2021-02-16       Impact factor: 3.850

5.  Prognostic value of HLA class I expression in patients with oral squamous cell carcinoma.

Authors:  Kazushige Koike; Hironari Dehari; Shota Shimizu; Koyo Nishiyama; Tomoko Sonoda; Kazuhiro Ogi; Junichi Kobayashi; Takanori Sasaki; Takashi Sasaya; Kei Tsuchihashi; Tomohide Tsukahara; Tadashi Hasegawa; Toshihiko Torigoe; Hiroyoshi Hiratsuka; Akihiro Miyazaki
Journal:  Cancer Sci       Date:  2020-04-15       Impact factor: 6.716

6.  Tissue-infiltrating immune cells as prognostic markers in oral squamous cell carcinoma: a systematic review and meta-analysis.

Authors:  Elin Hadler-Olsen; Anna Maria Wirsing
Journal:  Br J Cancer       Date:  2019-02-27       Impact factor: 7.640

7.  Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology.

Authors:  Inês Sequeira; Mamunur Rashid; Inês M Tomás; Marc J Williams; Trevor A Graham; David J Adams; Alessandra Vigilante; Fiona M Watt
Journal:  Nat Commun       Date:  2020-11-09       Impact factor: 14.919

8.  Prognostic signature related to the immune environment of oral squamous cell carcinoma.

Authors:  Yingjie Hua; Xuehui Sun; Kefeng Luan; Changlei Wang
Journal:  Open Life Sci       Date:  2022-09-14       Impact factor: 1.311

9.  Immunomodulatory role of Keratin 76 in oral and gastric cancer.

Authors:  Inês Sequeira; Joana F Neves; Dido Carrero; Qi Peng; Natalia Palasz; Kifayathullah Liakath-Ali; Graham M Lord; Peter R Morgan; Giovanna Lombardi; Fiona M Watt
Journal:  Nat Commun       Date:  2018-08-24       Impact factor: 14.919
  9 in total

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