Literature DB >> 27083339

Enhancement of anti-inflammatory activity of bromelain by its encapsulation in katira gum nanoparticles.

Manju Bernela1, Munish Ahuja2, Rajesh Thakur3.   

Abstract

Bromelain-loaded katira gum nanoparticles were synthesized using 3 level optimization process and desirability approach. Nanoparticles of the optimized batch were characterized using particle size analysis, zeta potential, transmission electron microscopy and Fourier-transform infrared spectroscopy. Investigation of their in vivo anti-inflammatory activity by employing carrageenan induced rat-paw oedema method showed that encapsulation of bromelain in katira gum nanoparticles substantially enhanced its anti-inflammatory potential. This may be attributed to enhanced absorption owing to reduced particle size or to protection of bromelain from acid proteases.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Bromelain; Cochlospermum religiosum; FTIR; Katira gum; Nanoparticles

Mesh：

Substances：

Year:  2016        PMID： 27083339     DOI： 10.1016/j.carbpol.2016.01.055

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN： 0144-8617            Impact factor:   9.381


  6 in total

1.  Bromelain Loaded Lipid-Polymer Hybrid Nanoparticles for Oral Delivery: Formulation and Characterization.

Authors:  Mahboubeh Ebrahimian; Fatemeh Mahvelati; Bizhan Malaekeh-Nikouei; Ezzat Hashemi; Fatemeh Oroojalian; Maryam Hashemi
Journal:  Appl Biochem Biotechnol       Date:  2022-05-04       Impact factor: 3.094

2.  Anti-Inflammatory Activity of Bullfrog Oil Polymeric Nanocapsules: From the Design to Preclinical Trials.

Authors:  Lucas Amaral-Machado; Wógenes N Oliveira; Manoela Torres-Rêgo; Allanny A Furtado; Éverton N Alencar; Matheus F Fernandes-Pedrosa; Hugo A O Rocha; Eryvaldo Sócrates Tabosa Egito
Journal:  Int J Nanomedicine       Date:  2021-11-02

Review 3.  Recent Progress on Modified Gum Katira Polysaccharides and Their Various Potential Applications.

Authors:  Mahendra Singh; Chaitany Jayprakash Raorane; Divya Shastri; Vinit Raj; Seong-Cheol Kim; Minkal Tuteja
Journal:  Polymers (Basel)       Date:  2022-09-02       Impact factor: 4.967

4.  Encapsulation of Bromelain in Combined Sodium Alginate and Amino Acid Carriers: Experimental Design of Simplex-Centroid Mixtures for Digestibility Evaluation.

Authors:  Philipi Cavalcante Ricardo; Ricardo Lima Serudo; Ştefan Ţălu; Carlos Victor Lamarão; Henrique Duarte da Fonseca Filho; Jaqueline de Araújo Bezerra; Edgar Aparecido Sanches; Pedro Henrique Campelo
Journal:  Molecules       Date:  2022-09-27       Impact factor: 4.927

5.  Enhancement of the Anti-inflammatory Effect of Bromelain by Its Immobilization on Probiotic Spore of Bacillus cereus.

Authors:  Chika Jude Ugwuodo; Tochukwu Nwamaka T Nwagu; Tochukwu Thaddeus Ugwu; Chukwudi Ogbonnaya Onwosi
Journal:  Probiotics Antimicrob Proteins       Date:  2020-11-06       Impact factor: 4.609

Review 6.  Bromelain and Nisin: The Natural Antimicrobials with High Potential in Biomedicine.

Authors:  Urška Jančič; Selestina Gorgieva
Journal:  Pharmaceutics       Date:  2021-12-29       Impact factor: 6.321
  6 in total

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