Literature DB >> 27082827

Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of β-Cell Replacement.

James F Markmann1, Stephen T Bartlett, Paul Johnson, Olle Korsgren, Bernhard J Hering, David Scharp, Thomas W H Kay, Jonathan Bromberg, Jon S Odorico, Gordon C Weir, Nancy Bridges, Raja Kandaswamy, Peter Stock, Peter Friend, Mitsukazu Gotoh, David K C Cooper, Chung-Gyu Park, Philip J OʼConnell, Cherie Stabler, Shinichi Matsumoto, Barbara Ludwig, Pratik Choudhary, Boris Khovatchev, Michael R Rickels, Megan Sykes, Kathryn Wood, Kristy Kraemer, Albert Hwa, Edward Stanley, Camillo Ricordi, Mark Zimmerman, Julia Greenstein, Eduard Montanya, Timo Otonkoski.   

Abstract

The International Pancreas and Islet Transplant Association (IPITA), in conjunction with the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.

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Year:  2016        PMID: 27082827     DOI: 10.1097/TP.0000000000001054

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  10 in total

Review 1.  Pig-to-Primate Islet Xenotransplantation: Past, Present, and Future.

Authors:  Zhengzhao Liu; Wenbao Hu; Tian He; Yifan Dai; Hidetaka Hara; Rita Bottino; David K C Cooper; Zhiming Cai; Lisha Mou
Journal:  Cell Transplant       Date:  2017-02-03       Impact factor: 4.064

Review 2.  Progress in Clinical Encapsulated Islet Xenotransplantation.

Authors:  David K C Cooper; Shinichi Matsumoto; Adrian Abalovich; Takeshi Itoh; Nizar I Mourad; Pierre R Gianello; Eckhard Wolf; Emanuele Cozzi
Journal:  Transplantation       Date:  2016-11       Impact factor: 4.939

Review 3.  Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop.

Authors:  Michael R Rickels; Peter G Stock; Eelco J P de Koning; Lorenzo Piemonti; Johann Pratschke; Rodolfo Alejandro; Melena D Bellin; Thierry Berney; Pratik Choudhary; Paul R Johnson; Raja Kandaswamy; Thomas W H Kay; Bart Keymeulen; Yogish C Kudva; Esther Latres; Robert M Langer; Roger Lehmann; Barbara Ludwig; James F Markmann; Marjana Marinac; Jon S Odorico; François Pattou; Peter A Senior; James A M Shaw; Marie-Christine Vantyghem; Steven White
Journal:  Transplantation       Date:  2018-09       Impact factor: 4.939

Review 4.  Progress in xenotransplantation: overcoming immune barriers.

Authors:  Megan Sykes; David H Sachs
Journal:  Nat Rev Nephrol       Date:  2022-10-05       Impact factor: 42.439

5.  International Survey of Clinical Monitoring Practices in Pancreas and Islet Transplantation.

Authors:  Casey Ward; Jon S Odorico; Michael R Rickels; Thierry Berney; George W Burke; Thomas W H Kay; Olivier Thaunat; Pablo D Uva; Eelco J P de Koning; Helmut Arbogast; Hanne Scholz; Mark S Cattral; Robert J Stratta; Peter G Stock
Journal:  Transplantation       Date:  2022-07-22       Impact factor: 5.385

Review 6.  Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.

Authors:  Michael R Rickels; Peter G Stock; Eelco J P de Koning; Lorenzo Piemonti; Johann Pratschke; Rodolfo Alejandro; Melena D Bellin; Thierry Berney; Pratik Choudhary; Paul R Johnson; Raja Kandaswamy; Thomas W H Kay; Bart Keymeulen; Yogish C Kudva; Esther Latres; Robert M Langer; Roger Lehmann; Barbara Ludwig; James F Markmann; Marjana Marinac; Jon S Odorico; François Pattou; Peter A Senior; James A M Shaw; Marie-Christine Vantyghem; Steven White
Journal:  Transpl Int       Date:  2018-04       Impact factor: 3.782

7.  Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes.

Authors:  Barbara Ludwig; Stefan Ludwig; Anja Steffen; Yvonne Knauf; Baruch Zimerman; Sophie Heinke; Susann Lehmann; Undine Schubert; Janine Schmid; Martina Bleyer; Uwe Schönmann; Clark K Colton; Ezio Bonifacio; Michele Solimena; Andreas Reichel; Andrew V Schally; Avi Rotem; Uriel Barkai; Helena Grinberg-Rashi; Franz-Josef Kaup; Yuval Avni; Peter Jones; Stefan R Bornstein
Journal:  Proc Natl Acad Sci U S A       Date:  2017-10-16       Impact factor: 11.205

Review 8.  Transplanting organs from pigs to humans.

Authors:  Megan Sykes; David H Sachs
Journal:  Sci Immunol       Date:  2019-11-01

9.  Clinical Islet Xenotransplantation: A Step Forward.

Authors:  Burcin Ekser; Rita Bottino; David K C Cooper
Journal:  EBioMedicine       Date:  2016-09-24       Impact factor: 8.143

10.  Conformal Coating of Stem Cell-Derived Islets for β Cell Replacement in Type 1 Diabetes.

Authors:  Aaron A Stock; Vita Manzoli; Teresa De Toni; Maria M Abreu; Yeh-Chuin Poh; Lillian Ye; Adam Roose; Felicia W Pagliuca; Chris Thanos; Camillo Ricordi; Alice A Tomei
Journal:  Stem Cell Reports       Date:  2019-12-12       Impact factor: 7.765

  10 in total

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