Literature DB >> 27078730

[The treatment of tuberculosis].

Thomas Degen1, Thomas Bregenzer2.   

Abstract

The incidence of tuberculosis decreases. However, clinical cases frequently raise questions, mainly in the context of contact tracing or when antimicrobial resistance is suspected. Empiric standard treatment consists of rifampin, isoniazid, ethambutol and pyrazinamide. This initial regimen aims to reduce the number of pathogenic germs while the consolidation therapy should eradicate the remaining pathogens. Treatment duration and adherence are crucial for cure. For the treatment of latent tuberculosis the traditional 6 to 9 months isoniazid regimen is still the treatment of choice. In complex cases such as tuberculosis in immunocompromised patients or if resistant tuberculosis is suspected, patients should be referred to a specialized center.

Entities:  

Keywords:  DOT; Resistenz; Therapieadhärenz; adherence; adhérence au traitement; antituberculous treatment; antituberkulöse Therapie; resistance; résistance; traitement antituberculeux

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Year:  2016        PMID: 27078730     DOI: 10.1024/1661-8157/a002322

Source DB:  PubMed          Journal:  Praxis (Bern 1994)        ISSN: 1661-8157


  2 in total

1.  Mutations in catalase-peroxidase KatG from isoniazid resistant Mycobacterium tuberculosis clinical isolates: insights from molecular dynamics simulations.

Authors:  Arethusa Lobo Pimentel; Regiane Bertin de Lima Scodro; Katiany Rizzieri Caleffi-Ferracioli; Vera Lúcia Dias Siqueira; Paula Aline Zanetti Campanerut-Sá; Luciana Dias Ghiraldi Lopes; Aryadne Larissa de Almeida; Rosilene Fressatti Cardoso; Flavio Augusto Vicente Seixas
Journal:  J Mol Model       Date:  2017-03-16       Impact factor: 1.810

2.  Contribution of Computed Tomography Scan to the Diagnosis of Spinal Tuberculosis in 14 Cases in Assaba, Mauritania.

Authors:  Boushab Mohamed Boushab; Noukhoum Kone; Leonardo K Basco
Journal:  Radiol Res Pract       Date:  2019-05-02
  2 in total

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