| Literature DB >> 27078124 |
Ren-Rong Liu1, Bao-Le Li1, Jun Lu1, Chong Shen1, Jian-Rong Gao1, Yi-Xia Jia1.
Abstract
A highly enantioselective palladium/l-proline-catalyzed α-arylative desymmetrization of cyclohexanones was developed. The new strategy for α-arylation reaction led to a series of optically active morphan derivatives bearing α-carbonyl tertiary stereocenters in good yields with excellent enantioselectivities (up to 99% ee).Entities:
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Year: 2016 PMID： 27078124 DOI： 10.1021/jacs.6b01214
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419