CONTEXT: Spinal cord injury (SCI) affects more than 2.5 million people worldwide, often leading to severe disability. Thus, a proper management of individuals with SCI is required either in the acute or in the post-acute rehabilitative phase. FINDINGS: A 31-year-old man, affected by chronic SCI, underwent two different intensive rehabilitation treatments, including either LokomatPro or a paired LokomatPro-rTMS training. We evaluated the clinical, kinetic, and electrophysiological parameters before and after each training session. In particular, the intensive robotic training was articulated in a total of 40 one-hour training sessions (i.e. 5 times a week for 8 weeks), whereas the rTMS sessions were delivered 3 days per week for 3 consecutive weeks, just before the LokomatPro session. Only at the end of the experimental treatment, we observed an important improvement in nearly all parameters we investigated. CLINICAL RELEVANCE: The combined LokomatPro-rTMS rehabilitation may be a valuable approach in improving the motor function in patients affected by SCI, even in the chronic phase.
CONTEXT: Spinal cord injury (SCI) affects more than 2.5 million people worldwide, often leading to severe disability. Thus, a proper management of individuals with SCI is required either in the acute or in the post-acute rehabilitative phase. FINDINGS: A 31-year-old man, affected by chronic SCI, underwent two different intensive rehabilitation treatments, including either LokomatPro or a paired LokomatPro-rTMS training. We evaluated the clinical, kinetic, and electrophysiological parameters before and after each training session. In particular, the intensive robotic training was articulated in a total of 40 one-hour training sessions (i.e. 5 times a week for 8 weeks), whereas the rTMS sessions were delivered 3 days per week for 3 consecutive weeks, just before the LokomatPro session. Only at the end of the experimental treatment, we observed an important improvement in nearly all parameters we investigated. CLINICAL RELEVANCE: The combined LokomatPro-rTMS rehabilitation may be a valuable approach in improving the motor function in patients affected by SCI, even in the chronic phase.
Authors: James E Graham; Carl V Granger; Amol M Karmarkar; Anne Deutsch; Paulette Niewczyk; Margaret A Divita; Kenneth J Ottenbacher Journal: Am J Phys Med Rehabil Date: 2014-03 Impact factor: 2.159
Authors: Nuray Yozbatiran; Zafer Keser; Khader Hasan; Argyrios Stampas; Radha Korupolu; Sam Kim; Marcia K O'Malley; Felipe Fregni; Gerard E Francisco Journal: Spinal Cord Ser Cases Date: 2017-06-15
Authors: Amanda Vitória Lacerda de Araújo; Valéria Ribeiro Nogueira Barbosa; Gilma Serra Galdino; Felipe Fregni; Thais Massetti; Sara Lynn Fontes; Danilo de Oliveira Silva; Talita Dias da Silva; Carlos Bandeira de Mello Monteiro; James Tonks; Fernando Henrique Magalhães Journal: Trials Date: 2017-11-06 Impact factor: 2.279
Authors: Neha Singh; Megha Saini; Nand Kumar; M V Padma Srivastava; S Senthil Kumaran; Amit Mehndiratta Journal: Front Neurol Date: 2021-07-12 Impact factor: 4.003