Xiaodong Zhuang1, You Peng1, Adham Sameer A Bardeesi1, Ekhlas Samir A Bardisi1, Xinxue Liao1, Chufan Luo1. 1. 1 Department of Cardiology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China ; 2 Department of Geriatric, Geriatric Hospital of Hunan Province, Changsha, China ; 3 Department of Surgery, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia ; 4 Department of Surgery, University hospitals Leuven (UZ-Leuven), Leuven, Belgium.
Abstract
BACKGROUND: The vessel heterogeneity of thrombolysis in myocardial infarction (TIMI) frame count (TFC) in patients with coronary slow flow (CSF) remains to be further evaluated, and the correlation between TFC heterogeneity and P-wave dispersion (PWD) has not been elucidated. We aim to investigate the vessel heterogeneity of TFC in coronary arteries, and its relation to PWD in patients with CSF and otherwise normal coronary arteries. METHODS: We studied 72 patients with angiographically documented CSF and 66 age- and gender-matched control subjects. The coefficient of variation (CV) and mean TFC of the three vessels were calculated. P-wave duration and PWD were measured on the standard electrocardiograms (ECGs). RESULTS: The mean TFC and CV were both significantly higher in CSF patients than in controls (P<0.001 for both comparisons). The maximum P-wave duration (Pmax) and PWD were found to be significantly higher in CSF patients than in controls (P<0.001 for both comparisons). In patients with CSF, both Pmax and PWD were mildly correlated to mean TFC (r=0.318, P=0.009; and r=0.307, P=0.010), and were more significantly correlated to CV (r=0.506, P<0.001; and r=0.579, P<0.001). CONCLUSIONS: These data demonstrate that variability of TFC in three coronary arteries is increased in CSF patients, and that the vessel heterogeneity in coronary flow might be intimately associated with PWD.
BACKGROUND: The vessel heterogeneity of thrombolysis in myocardial infarction (TIMI) frame count (TFC) in patients with coronary slow flow (CSF) remains to be further evaluated, and the correlation between TFC heterogeneity and P-wave dispersion (PWD) has not been elucidated. We aim to investigate the vessel heterogeneity of TFC in coronary arteries, and its relation to PWD in patients with CSF and otherwise normal coronary arteries. METHODS: We studied 72 patients with angiographically documented CSF and 66 age- and gender-matched control subjects. The coefficient of variation (CV) and mean TFC of the three vessels were calculated. P-wave duration and PWD were measured on the standard electrocardiograms (ECGs). RESULTS: The mean TFC and CV were both significantly higher in CSF patients than in controls (P<0.001 for both comparisons). The maximum P-wave duration (Pmax) and PWD were found to be significantly higher in CSF patients than in controls (P<0.001 for both comparisons). In patients with CSF, both Pmax and PWD were mildly correlated to mean TFC (r=0.318, P=0.009; and r=0.307, P=0.010), and were more significantly correlated to CV (r=0.506, P<0.001; and r=0.579, P<0.001). CONCLUSIONS: These data demonstrate that variability of TFC in three coronary arteries is increased in CSF patients, and that the vessel heterogeneity in coronary flow might be intimately associated with PWD.
Authors: Oscar C Marroquin; Richard Holubkov; Daniel Edmundowicz; Cheryl Rickens; Gerald Pohost; Steven Buchthal; Carl J Pepine; George Sopko; Robert C Sembrat; Carolyn Cidis Meltzer; Steven E Reis Journal: Am Heart J Date: 2003-04 Impact factor: 4.749
Authors: K Aytemir; N Ozer; E Atalar; E Sade; S Aksöyek; K Ovünç; A Oto; F Ozmen; S Kes Journal: Pacing Clin Electrophysiol Date: 2000-07 Impact factor: 1.976