Literature DB >> 27075238

Hemoglobin Differences in Uncomplicated Monochorionic Twins in Relation to Birth Order and Mode of Delivery.

Lianne Verbeek1, Depeng P Zhao1, Arjan B Te Pas1, Johanna M Middeldorp2, Stuart B Hooper3, Dick Oepkes2, Enrico Lopriore1.   

Abstract

AIM: To determine the differences in hemoglobin (Hb) levels in the first 2 days after birth in uncomplicated monochorionic twins in relation to birth order and mode of delivery.
METHODS: All consecutive uncomplicated monochorionic pregnancies with two live-born twins delivered at our center were included in this retrospective study. We recorded Hb levels at birth and on day 2, and analyzed Hb levels in association with birth order, mode of delivery, and time interval between delivery of twin 1 and 2.
RESULTS: A total of 290 monochorionic twin pairs were analyzed, including 171 (59%) twins delivered vaginally and 119 (41%) twins born by cesarean section (CS). In twins delivered vaginally, mean Hb levels at birth and on day 2 were significantly higher in second-born twins compared to first-born twins: 17.8 versus 16.1 g/dL and 18.0 versus 14.8 g/dL, respectively (p < .01). Polycythemia was detected more often in second-born twins (12%, 20/166) compared to first-born twins (1%, 2/166; p < .01). Hb differences within twin pairs delivered by CS were not statistically or clinically significant. We found no association between inter-twin delivery time intervals and Hb differences.
CONCLUSIONS: Second-born twins after vaginal delivery have higher Hb levels and more often polycythemia than their co-twin, but not when born by CS.

Entities:  

Keywords:  Monochorionic twins; cesarean section; hemoglobin; umbilical cord clamping; vaginal delivery

Mesh:

Substances:

Year:  2016        PMID: 27075238     DOI: 10.1017/thg.2016.23

Source DB:  PubMed          Journal:  Twin Res Hum Genet        ISSN: 1832-4274            Impact factor:   1.587


  2 in total

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Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2017-12-05       Impact factor: 5.747

2.  Hemoglobin differences in twins are related to the time of cord clamping, not intertwin transfusion - a prospective cohort study.

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Journal:  BMC Pregnancy Childbirth       Date:  2022-08-05       Impact factor: 3.105

  2 in total

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