Fredrik Karpe1, Cecilia M Lindgren1. 1. From the Oxford Centre for Diabetes, Endocrinology, and Metabolism, Radcliffe Department of Medicine, and the National Institute for Health Research Oxford Biomedical Research Centre (F.K.), and the Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, and the Li Ka Shing Centre for Health Information and Discovery, the Big Data Institute (C.M.L.), University of Oxford, Oxford, United Kingdom.