Literature DB >> 27073975

Understanding Early Decisions to Withdraw Life-Sustaining Therapy in Cardiac Arrest Survivors. A Qualitative Investigation.

Craig M Dale1,2, Tasnim Sinuff3,4, Laurie J Morrison5,6, Eyal Golan3,7,8, Damon C Scales3,7,4,9.   

Abstract

RATIONALE: Early withdrawal of life-sustaining therapy contributes to the majority of deaths following out-of-hospital cardiac arrest (OHCA), despite current recommendations for delayed neurological prognostication (≥72 h) after treatment with targeted temperature management. Little is known about clinicians' experiences of early withdrawal of life support decisions in patients with OHCA.
OBJECTIVES: To explore clinicians' experiences and perceptions of early withdrawal of life support decisions and barriers to guideline-concordant neurological prognostication in comatose survivors of OHCA treated with targeted temperature management.
METHODS: We conducted qualitative interviews with intensive care unit (ICU) physicians and nurses following withdrawal of life support in comatose patients with OHCA treated with targeted temperature management. The study was carried out across 18 academic and community hospitals participating in a multicenter, stepped-wedge, cluster-randomized controlled trial designed to improve quality-of-care processes for patients after OHCA in Ontario, Canada. We used a focused thematic analysis to capture barriers to guideline-concordant neurological prognostication and used these barriers to identify potentially modifiable issues.
MEASUREMENTS AND MAIN RESULTS: The core thematic finding was a high emotional burden of ICU family-team communication in which strong feelings inhibited information transfer and delayed decision making following OHCA. Four subthemes describing sources of communication strain were identified: (1) requests from family members to provide early outcome predictions, (2) incomplete family comprehension of critical care, (3) family requests for early withdrawal of life support based on their understanding of patients' preferences and values, and (4) family-team communication gaps related to prognostic uncertainty. Participants worried that gaps in timely and clear prognostic information contributed to surrogates' perceptions of a poor outcome and to inappropriately early decisions to withdraw life support.
CONCLUSIONS: Family-team communication difficulties may be an underestimated factor leading to early withdrawal of life support in ICUs for individuals who initially survive OHCA.

Entities:  

Keywords:  comatose patient; induced hypothermia; out-of-hospital cardiac arrest; prognostication; qualitative research

Mesh:

Year:  2016        PMID: 27073975     DOI: 10.1513/AnnalsATS.201511-751OC

Source DB:  PubMed          Journal:  Ann Am Thorac Soc        ISSN: 2325-6621


  9 in total

1.  Exploring Providers' Perspectives on Early Decisions to Withdraw Life-Sustaining Therapy after Cardiac Arrest. One Side of the Story.

Authors:  Sarah M Perman; Edward P Havranek
Journal:  Ann Am Thorac Soc       Date:  2016-07

2.  Out of Hospital Cardiac Arrest: A Current Review of the Literature that Informed the 2015 American Heart Association Guidelines Update.

Authors:  Melissa Milan; Sarah M Perman
Journal:  Curr Emerg Hosp Med Rep       Date:  2016-11-03

3.  Early withdrawal of life support after resuscitation from cardiac arrest is common and may result in additional deaths.

Authors:  Teresa L May; Robin Ruthazer; Richard R Riker; Hans Friberg; Nainesh Patel; Eldar Soreide; Robert Hand; Pascal Stammet; Allison Dupont; Karen G Hirsch; Sachin Agarwal; Michael J Wanscher; Josef Dankiewicz; Niklas Nielsen; David B Seder; David M Kent
Journal:  Resuscitation       Date:  2019-03-02       Impact factor: 5.262

4.  Prognostication in Acute Neurological Emergencies.

Authors:  Kelly L Sloane; Julie J Miller; Amanda Piquet; Brian L Edlow; Eric S Rosenthal; Aneesh B Singhal
Journal:  J Stroke Cerebrovasc Dis       Date:  2022-01-07       Impact factor: 2.136

5.  Withdrawal of Life-Sustaining Treatments in Perceived Devastating Brain Injury: The Key Role of Uncertainty.

Authors:  Christos Lazaridis
Journal:  Neurocrit Care       Date:  2019-02       Impact factor: 3.210

Review 6.  Management of Out-of-Hospital Cardiac Arrest Complicating Acute Coronary Syndromes.

Authors:  Sean M Bell; Christopher Kovach; Akash Kataruka; Josiah Brown; Ravi S Hira
Journal:  Curr Cardiol Rep       Date:  2019-11-22       Impact factor: 2.931

7.  European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post-resuscitation care.

Authors:  Jerry P Nolan; Claudio Sandroni; Bernd W Böttiger; Alain Cariou; Tobias Cronberg; Hans Friberg; Cornelia Genbrugge; Kirstie Haywood; Gisela Lilja; Véronique R M Moulaert; Nikolaos Nikolaou; Theresa Mariero Olasveengen; Markus B Skrifvars; Fabio Taccone; Jasmeet Soar
Journal:  Intensive Care Med       Date:  2021-03-25       Impact factor: 17.440

8.  Prediction of Neurological Outcomes in Out-of-hospital Cardiac Arrest Survivors Immediately after Return of Spontaneous Circulation: Ensemble Technique with Four Machine Learning Models.

Authors:  Ji Han Heo; Taegyun Kim; Jonghwan Shin; Gil Joon Suh; Joonghee Kim; Yoon Sun Jung; Seung Min Park; Sungwan Kim
Journal:  J Korean Med Sci       Date:  2021-07-19       Impact factor: 2.153

9.  Frequency of Withdrawal of Life-Sustaining Therapy for Perceived Poor Neurologic Prognosis.

Authors:  Alexis Steinberg; Benjamin S Abella; Emily J Gilmore; David Y Hwang; Niki Kennedy; Winnie Lau; Isabelle Mullen; Nidhi Ravishankar; Charlotte F Tisch; Adam Waddell; David J Wallace; Qiang Zhang; Jonathan Elmer
Journal:  Crit Care Explor       Date:  2021-07-13
  9 in total

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