Literature DB >> 2707378

Effects of enterally- and parenterally-administered bombesin on intestinal luminal tryptic activity and protein in the suckling rat.

P F Pollack1, C Adamson, O Koldovsky.   

Abstract

Because of the presence of bombesin-like immunoreactivity in milk, we investigated if enteral administration of bombesin affects the intestinal luminal content of trypsin and protein in 12-14-day-old rats. Bombesin (40 micrograms/kg), given either orogastrically or subcutaneously, produced a significant elevation in the intestinal content of trypsin activity. Thus, enterally-administered bombesin can produce acute biologic effects in suckling rats.

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Year:  1989        PMID: 2707378     DOI: 10.1007/BF01957488

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  20 in total

1.  In vitro action of bombesin and bombesin-like peptides on amylase secretion, calcium efflux, and adenylate cyclase activity in the rat pancreas: a comparison with other secretagogues.

Authors:  M Deschodt-Lanckman; P Robberecht; P De Neef; M Lammens; J Christophe
Journal:  J Clin Invest       Date:  1976-10       Impact factor: 14.808

Review 2.  Hormones in milk.

Authors:  O Koldovský; W Thornburg
Journal:  J Pediatr Gastroenterol Nutr       Date:  1987 Mar-Apr       Impact factor: 2.839

3.  Regulation of antral gastrin content.

Authors:  L R Johnson; P D Guthrie
Journal:  Am J Physiol       Date:  1983-12

4.  A bombesin immunoreactive peptide in milk.

Authors:  G D Jahnke; L H Lazarus
Journal:  Proc Natl Acad Sci U S A       Date:  1984-01       Impact factor: 11.205

5.  Intestinal uptake of trypsin in newborn and weaned rabbits.

Authors:  J N Udall; K J Bloch; A P Newman; M Dixon; W A Walker
Journal:  Am J Physiol       Date:  1984-08

6.  Induction of enterokinase in the rat small intestine following hypersecretion of trypsinogen by chronic trypsin inhibitor feeding.

Authors:  H Kai; H Tajiri; P C Lee; E Lebenthal
Journal:  J Pediatr Gastroenterol Nutr       Date:  1984-06       Impact factor: 2.839

7.  Effect of epidermal growth factor on ontogeny of the gastrointestinal tract.

Authors:  E V O'Loughlin; M Chung; M Hollenberg; J Hayden; I Zahavi; D G Gall
Journal:  Am J Physiol       Date:  1985-12

8.  Importance of bile in regulation of intraluminal proteolytic enzyme activities in the rat.

Authors:  G M Green; E S Nasset
Journal:  Gastroenterology       Date:  1980-10       Impact factor: 22.682

9.  Bombesin, neurotensin and pro-gamma-melanotropin immunoreactants in human milk.

Authors:  R Ekman; S Ivarsson; L Jansson
Journal:  Regul Pept       Date:  1985-03

10.  Effects of decapeptide of mammalian bombesin and neuromedin B on pancreatic exocrine secretion in the rat.

Authors:  M Namba; M A Ghatei; M Ghiglione; S R Bloom
Journal:  Digestion       Date:  1986       Impact factor: 3.216

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