Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Prothymosin alpha is not a nuclear polypeptide.

Literature DB >> 2707372

Prothymosin alpha is not a nuclear polypeptide.

O E Tsitsiloni¹, P P Yialouris, K Sekeri-Pataryas, A A Haritos.

Abstract

Using a radioimmunoassay for the NH2-terminus of prothymosin alpha, the crossreactive material was measured in subcellular fractions of calf thymus and liver. No significant amount of crossreactive material was found in the nucleus. This provides experimental evidence against a recent hypothesis, based on structural evidence, that prothymosin alpha is a nuclear polypeptide.

Entities: Gene Species

Mesh：

Substances：

Year: 1989 PMID： 2707372 DOI： 10.1007/BF01957467

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

17 in total

1. The amino acid sequence of bovine thymus prothymosin alpha.

Authors: C Panneerselvam; D Wellner; B L Horecker
Journal: Arch Biochem Biophys Date: 1988-09 Impact factor: 4.013

2. Prothymosin alpha is a nuclear protein.

Authors: J Gómez-Márquez; F Segade
Journal: FEBS Lett Date: 1988-01-04 Impact factor: 4.124

3. Immunolocalization of thymosin alpha 1, thymopoietin and thymulin in mouse thymic epithelial cells at different stages of culture: a light and electron microscopic study.

Authors: N Fabien; C Auger; J C Monier
Journal: Immunology Date: 1988-04 Impact factor: 7.397

4. Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1.

Authors: J E McClure; N Lameris; D W Wara; A L Goldstein
Journal: J Immunol Date: 1982-01 Impact factor: 5.422

5. Utilization of the citric acid procedure and zonal ultracentrifugation for mass isolation of nuclear RNA from Walker 256 carcinosarcoma.

Authors: K Higashi; K S Narayanan; H R Adams; H Busch
Journal: Cancer Res Date: 1966-07 Impact factor: 12.701

6. Human prothymosin alpha: amino acid sequence and immunologic properties.

Authors: L X Pan; A A Haritos; J Wideman; T Komiyama; M Chang; S Stein; S B Salvin; B L Horecker
Journal: Arch Biochem Biophys Date: 1986-10 Impact factor: 4.013

7. Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus.

Authors: A A Haritos; G J Goodall; B L Horecker
Journal: Proc Natl Acad Sci U S A Date: 1984-02 Impact factor: 11.205

8. Distribution of prothymosin alpha in rat tissues.

Authors: A A Haritos; O Tsolas; B L Horecker
Journal: Proc Natl Acad Sci U S A Date: 1984-03 Impact factor: 11.205

9. The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA.

Authors: W H Eschenfeldt; S L Berger
Journal: Proc Natl Acad Sci U S A Date: 1986-12 Impact factor: 11.205

10. Simultaneous isolation and determination of prothymosin alpha, parathymosin alpha, thymosin beta 4, and thymosin beta 10.

Authors: A A Haritos; J Caldarella; B L Horecker
Journal: Anal Biochem Date: 1985-02-01 Impact factor: 3.365

5 in total

Prothymosin alpha is not a nuclear polypeptide.

1. The amino acid sequence of bovine thymus prothymosin alpha.

2. Prothymosin alpha is a nuclear protein.

3. Immunolocalization of thymosin alpha 1, thymopoietin and thymulin in mouse thymic epithelial cells at different stages of culture: a light and electron microscopic study.

4. Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1.

5. Utilization of the citric acid procedure and zonal ultracentrifugation for mass isolation of nuclear RNA from Walker 256 carcinosarcoma.

6. Human prothymosin alpha: amino acid sequence and immunologic properties.

7. Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus.

8. Distribution of prothymosin alpha in rat tissues.

9. The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA.

10. Simultaneous isolation and determination of prothymosin alpha, parathymosin alpha, thymosin beta 4, and thymosin beta 10.

1. Evidence for the extranuclear localization of thymosins in thymus.

2. Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ.

3. Immunohistochemical location of prothymosin alpha in regenerating human hepatocytes and hepatocellular carcinomas.

4. Prothymosin alpha expression is associated to cell division in rat testis.

Review 5. Prothymosin Alpha and Immune Responses: Are We Close to Potential Clinical Applications?