Serous cystadenoma of the pancreas with atypical clinical manifestations: A case report.

The present study reported a 4.8 cm space-occupying cystic solid mass of the pancreas, which caused recurrent bilateral lower back discomfort in a 60-year-old female. Combined with the clinical data, an impression of a solid-pseudopapillary neoplasm was generated prior to surgery. Abdominal exploration revealed splenic vessel encasement by the mass similar to the invasion observed in a malignant tumor. Distal pancreatectomy with splenectomy was subsequently performed. Grossly, the tumor was solid and consisted of numerous small cysts. Histopathological examination of the cystic solid mass revealed classic microcystic serous cystadenoma of the pancreas. These findings suggested that microcystic serous cystadenoma can exhibit atypical clinical manifestations. Asymptomatic patients with a small lesion (<4 cm) require imaging surveillance every 2 years; however, tumors >4 cm with atypical presentations require surgical resection.