A Rack1, B H Belohradsky1, R Grantzow2, D V Schweinitz2, T Pfluger3, B Kammer4, H Girschick5, D Horst6, U Wintergerst7. 1. Children's Hospital, Infectious Diseases and Immunology, University of Munich, Munich, Germany. 2. Children's Hospital, Pediatric Surgery, University of Munich, Munich, Germany. 3. Department of Nuclear Medicine, University of Munich, Munich, Germany. 4. Department of Pediatric Radiology, University of Munich, Munich, Germany. 5. Children's Hospital, Vivantes Klinik, Berlin, Germany. 6. Institute of Pathology, University of Munich, Munich, Germany. 7. Department of Pediatrics, Hospital of Braunau, Braunau, Austria. uwe.wintergerst@khbr.at.
Abstract
UNLABELLED: We report on four female adolescents, who presented with inflammatory symptoms. Extensive diagnostic workup revealed tumors on different locations. After surgical removal, clinical and laboratory signs of inflammation disappeared rapidly. On histology, the tumors showed a mixture of inflammatory cells characteristic of inflammatory pseudotumors in three of the patients. CONCLUSION: In patients with unclear inflammatory symptoms, inflammatory pseudotumor should be added to the differential diagnosis. WHAT IS KNOWN: • The inflammatory pseudotumor (IPT) is a mostly benign myofibroblastic tumor of the soft tissue and causes inflammatory symptoms. What is new: • IPTs have may wider than hitherto defined histologic features. Removal of IPT is curative.
UNLABELLED: We report on four female adolescents, who presented with inflammatory symptoms. Extensive diagnostic workup revealed tumors on different locations. After surgical removal, clinical and laboratory signs of inflammation disappeared rapidly. On histology, the tumors showed a mixture of inflammatory cells characteristic of inflammatory pseudotumors in three of the patients. CONCLUSION: In patients with unclear inflammatory symptoms, inflammatory pseudotumor should be added to the differential diagnosis. WHAT IS KNOWN: • The inflammatory pseudotumor (IPT) is a mostly benign myofibroblastic tumor of the soft tissue and causes inflammatory symptoms. What is new: • IPTs have may wider than hitherto defined histologic features. Removal of IPT is curative.
Authors: Martin W Huellner; Bernhard Schwizer; Irene Burger; Ingo Fengels; Reinhard Schläpfer; Christian Bussmann; Klaus Strobel Journal: Clin Nucl Med Date: 2010-09 Impact factor: 7.794
Authors: P Rohrlich; M Peuchmaur; S N Cocci; I D Gasselin; C Garel; Y Aigrain; P Galanaud; E Vilmer; D Emilie Journal: Am J Surg Pathol Date: 1995-05 Impact factor: 6.394