Christina Goll1, Markus Thormann2, Wolfram Hofmüller1, Björn Friebe2, Wolfgang Behrens-Baumann1, Thorsten A Bley3, Michael B Hoffmann4,5, Oliver Speck6,7,8. 1. Department of Ophthalmology, Visual Processing Laboratory, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany. 2. Department of Radiology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany. 3. Department of Diagnostic and Interventional Radiology, University Medical Center Würzburg, Würzburg, Germany. 4. Department of Ophthalmology, Visual Processing Laboratory, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany. michael.hoffmann@med.ovgu.de. 5. Center for Behavioral Brain Sciences, Magdeburg, Germany. michael.hoffmann@med.ovgu.de. 6. Center for Behavioral Brain Sciences, Magdeburg, Germany. 7. Department Biomedical Magnetic Resonance, Institute for Experimental Physics, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany. 8. Leibniz Institute for Neurobiology, Magdeburg, Germany.
Abstract
OBJECTIVES: To assess the detectability of vasculitic changes of the superficial cranial arteries with contrast-enhanced 7 T MRI in three patients with GCA and intraindividual comparison with 3 T MRI. METHODS: Three patients (two female, one male) with suspected GCA underwent contrast-enhanced T1-weighted high-resolution MRI at 3 T and 7 T magnetic field strength. The clinical diagnosis, based on criteria of the American College of Rheumatology, was confirmed by biopsy of the superficial temporal artery after MRI. MR images were visually assessed for detection of vasculitic mural contrast enhancement and vessel wall thickening of the superficial cranial arteries. RESULTS: Both 3 T and 7 T MRI allows for visualisation of mural inflammatory changes and assessment of the vasculitic involvement pattern. Image quality of 7 T MRI was rated superior to image quality of 3 T MRI scans. CONCLUSIONS: 7 T MR imaging of vasculitic changes in patients with GCA is possible, and suggests superior image quality. Larger patient studies are necessary to quantify the diagnostic advantages of 7 T MRI.
OBJECTIVES: To assess the detectability of vasculitic changes of the superficial cranial arteries with contrast-enhanced 7 T MRI in three patients with GCA and intraindividual comparison with 3 T MRI. METHODS: Three patients (two female, one male) with suspected GCA underwent contrast-enhanced T1-weighted high-resolution MRI at 3 T and 7 T magnetic field strength. The clinical diagnosis, based on criteria of the American College of Rheumatology, was confirmed by biopsy of the superficial temporal artery after MRI. MR images were visually assessed for detection of vasculitic mural contrast enhancement and vessel wall thickening of the superficial cranial arteries. RESULTS: Both 3 T and 7 T MRI allows for visualisation of mural inflammatory changes and assessment of the vasculitic involvement pattern. Image quality of 7 T MRI was rated superior to image quality of 3 T MRI scans. CONCLUSIONS: 7 T MR imaging of vasculitic changes in patients with GCA is possible, and suggests superior image quality. Larger patient studies are necessary to quantify the diagnostic advantages of 7 T MRI.
Entities:
Keywords:
Giant cell arteritis; Magnetic resonance imaging; Morbus Horton; Temporal arteries; Ultra-high field MRI; Vasculitis
Authors: T A Bley; M Uhl; J Carew; M Markl; D Schmidt; H-H Peter; M Langer; O Wieben Journal: AJNR Am J Neuroradiol Date: 2007-09-20 Impact factor: 3.825
Authors: Christian Dejaco; Elisabeth Brouwer; Justin C Mason; Frank Buttgereit; Eric L Matteson; Bhaskar Dasgupta Journal: Nat Rev Rheumatol Date: 2017-09-14 Impact factor: 20.543
Authors: Nathan Arnett; Athanasios Pavlou; Morgan P Burke; Brett L Cucchiara; Rennie L Rhee; Jae W Song Journal: Neuroradiology Date: 2021-05-03 Impact factor: 2.804