Hyun-Hae Cho1,2, Young Hun Choi1,3, Jung-Eun Cheon1,3,4, So Mi Lee1,5, Woo Sun Kim1,3,4, In-One Kim1,3,4, MunYoung Paek6. 1. 1 Department of Radiology, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 0380 Korea. 2. 2 Present address: Department of Radiology, Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea. 3. 3 Department of Radiology, Seoul National University College of Medicine, Seoul, Korea. 4. 4 Institute of Radiation Medicine, Seoul National University Medical Research Center, Seoul, Korea. 5. 5 Present address: Department of Radiology, Kyungpook National University Medical Center, Daegu, Korea. 6. 6 Siemens Healthcare, Seoul, Korea.
Abstract
OBJECTIVE: The purpose of this study was to compare free-breathing radially sampled 3D T1-weighted gradient-echo acquisitions (radial volumetric interpolated breath-hold examination [VIBE]) with a T1-weighted turbo spin-echo (TSE) sequence for contrast-enhanced spinal imaging of children with CNS tumors. MATERIALS AND METHODS: Twenty-eight consecutively registered children with CNS tumors underwent evaluation of leptomeningeal seeding with 1.5-T MRI that included both radial VIBE and T1-weighted TSE sequences. For qualitative analysis, overall image quality; presence of motion, CSF flow, and radial artifacts; and lesion conspicuity were retrospectively assessed with scoring systems. The signal-intensity uniformity of each sequence was evaluated for quantitative comparison. The acquisition times for each sequence were compared. RESULTS: Images obtained with the radial VIBE sequence had a higher overall image quality score than did T1-weighted TSE images (3.61 ± 0.73 vs 2.80 ± 0.69, p < 0.001) and lower motion artifact (0.82 ± 0.43 vs 1.29 ± 0.56, p = 0.001) and CSF flow artifact (0 vs 1.68 ± 0.67, p < 0.001) scores. Radial artifacts were found only on radial VIBE images (1.36 ± 0.31 vs 0, p < 0.001). In 13 patients with spinal seeding nodules, radial VIBE images showed greater lesion conspicuity than did T1-weighted TSE images (4.23 ± 0.52 vs 2.47 ± 0.57, p = 0.005). Radial VIBE images had diminished signal-intensity variation compared with T1-weighted TSE images in air, spine, and muscle (p < 0.01). The mean acquisition times were not significantly different between the two sequences (p = 0.117). CONCLUSION: For pediatric spinal imaging, radial VIBE images had better image quality and lesion conspicuity and fewer CSF and respiratory motion artifacts than did T1-weighted TSE images in a similar acquisition time.
OBJECTIVE: The purpose of this study was to compare free-breathing radially sampled 3D T1-weighted gradient-echo acquisitions (radial volumetric interpolated breath-hold examination [VIBE]) with a T1-weighted turbo spin-echo (TSE) sequence for contrast-enhanced spinal imaging of children with CNS tumors. MATERIALS AND METHODS: Twenty-eight consecutively registered children with CNS tumors underwent evaluation of leptomeningeal seeding with 1.5-T MRI that included both radial VIBE and T1-weighted TSE sequences. For qualitative analysis, overall image quality; presence of motion, CSF flow, and radial artifacts; and lesion conspicuity were retrospectively assessed with scoring systems. The signal-intensity uniformity of each sequence was evaluated for quantitative comparison. The acquisition times for each sequence were compared. RESULTS: Images obtained with the radial VIBE sequence had a higher overall image quality score than did T1-weighted TSE images (3.61 ± 0.73 vs 2.80 ± 0.69, p < 0.001) and lower motion artifact (0.82 ± 0.43 vs 1.29 ± 0.56, p = 0.001) and CSF flow artifact (0 vs 1.68 ± 0.67, p < 0.001) scores. Radial artifacts were found only on radial VIBE images (1.36 ± 0.31 vs 0, p < 0.001). In 13 patients with spinal seeding nodules, radial VIBE images showed greater lesion conspicuity than did T1-weighted TSE images (4.23 ± 0.52 vs 2.47 ± 0.57, p = 0.005). Radial VIBE images had diminished signal-intensity variation compared with T1-weighted TSE images in air, spine, and muscle (p < 0.01). The mean acquisition times were not significantly different between the two sequences (p = 0.117). CONCLUSION: For pediatric spinal imaging, radial VIBE images had better image quality and lesion conspicuity and fewer CSF and respiratory motion artifacts than did T1-weighted TSE images in a similar acquisition time.
Authors: Katherine E Warren; Gilbert Vezina; Tina Y Poussaint; Monika Warmuth-Metz; Marc C Chamberlain; Roger J Packer; Alba A Brandes; Moshe Reiss; Stewart Goldman; Michael J Fisher; Ian F Pollack; Michael D Prados; Patrick Y Wen; Susan M Chang; Christelle Dufour; David Zurakowski; Rolf D Kortmann; Mark W Kieran Journal: Neuro Oncol Date: 2018-01-10 Impact factor: 12.300