| Literature DB >> 27069334 |
Charu Yadav1, Afzal Ahmad1, Benedicta D'Souza1, Ashish Agarwal1, M Nandini1, K Ashok Prabhu1, Vivian D'Souza2.
Abstract
Non-Hodgkin's lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50-75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin's lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).Entities:
Keywords: Lactate dehydrogenase (LDH); Non-Hodgkin’s lymphoma (NHL)
Year: 2015 PMID： 27069334 PMCID： PMC4820421 DOI： 10.1007/s12291-015-0511-3
Source DB: PubMed Journal: Indian J Clin Biochem ISSN： 0970-1915