| Literature DB >> 270682 |
G R Kitchingman, S P Lai, H Westphal.
Abstract
Separated strands of adenovirus DNA were annealed with early cytoplasmic RNA and visualized in the electron microscope. DNA-RNA duplex regions within the DNA filaments could be recognized by their heavy contour. This contour was often interrupted at distinct locations by loops of displaced, single-stranded DNA. Loops have been observed and mapped in all four early regions of the genome. The structures appear to signal hitherto unknown mechanisms of eukaryotic gene expression.Mesh:
Substances:
Year: 1977 PMID: 270682 PMCID: PMC431948 DOI: 10.1073/pnas.74.10.4392
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205