Angela Mauro1, Marianna Fabi2, Monica Da Frè3, Paolo Guastaroba4, Elena Corinaldesi5, Giovanni Battista Calabri6, Teresa Giani7, Gabriele Simonini7, Franca Rusconi8, Rolando Cimaz7. 1. Department of Pediatrics, Second University of Naples, via Luigi De Crecchio, 80138, Naples, Italy. angela.mauro84@gmail.com. 2. Pediatric Cardiology and Cardiac Surgery, S. Orsola-Malpighi Hospital, University of Bologna, via Pietro Albertoni 15, 40138, Bologna, Italy. 3. Unit of Epidemiology, Regional Health Agency of Tuscany, Villa La Quiete alle Montalve, via Pietro Dazzi 1, 50141, Florence, Italy. 4. Agenzia Sanitaria e Sociale Regionale - Regione Emilia-Romagna, Area Governo Clinico, Viale A. Moro, 21-40127, Bologna, Italy. 5. Department of Pediatrics, Ramazzini Hospital, Via Guido Molinari, 2, 41012, Carpi, Italy. 6. Cardiology Unit, Anna Meyer Children's Hospital, Department of Pediatrics, University of Firenze, Viale Pieraccini 24, 50139, Florence, Italy. 7. Rheumatology Unit, Anna Meyer Children's Hospital, Department of Pediatrics, University of Firenze, Viale Pieraccini 24, 50139, Florence, Italy. 8. Epidemiology Unit, Anna Meyer Children's University Hospital, Viale Pieraccini 24, 50139, Florence, Italy.
Abstract
BACKGROUND: Kawasaki disease (KD) is a systemic vasculitis with an acute and self-limited course. The incidence of KD differs widely among ethnic groups and is higher in the Asian population. In Italy, no recent data are available. Our purpose is to define the epidemiology of Kawasaki disease in the years 2008-2013 in children aged < 14 years in the Italian regions of Tuscany and Emilia Romagna through administrative data. METHODS: We studied the epidemiology of KD in the years 2008-2013 in children 0-14 years old resident in Tuscany and in Emilia Romagna regions using hospital ICD-9 discharge codes with a thorough data cleaning for duplicates. RESULTS: The distribution of the KD patients across ages was similar for the two regions with a peak in the second year of life. When considering data of the two regions together, the rate of incidence was 17.6 for 100,000 children under 5 years. For both Regions the incidence rose slightly during the study period and had a seasonal distribution, with higher incidence in spring and winter. CONCLUSION: This is the first Italian study performed through the use of administrative data. Figures are in line but slightly higher than those published in other European countries.
BACKGROUND:Kawasaki disease (KD) is a systemic vasculitis with an acute and self-limited course. The incidence of KD differs widely among ethnic groups and is higher in the Asian population. In Italy, no recent data are available. Our purpose is to define the epidemiology of Kawasaki disease in the years 2008-2013 in children aged < 14 years in the Italian regions of Tuscany and Emilia Romagna through administrative data. METHODS: We studied the epidemiology of KD in the years 2008-2013 in children 0-14 years old resident in Tuscany and in Emilia Romagna regions using hospital ICD-9 discharge codes with a thorough data cleaning for duplicates. RESULTS: The distribution of the KDpatients across ages was similar for the two regions with a peak in the second year of life. When considering data of the two regions together, the rate of incidence was 17.6 for 100,000 children under 5 years. For both Regions the incidence rose slightly during the study period and had a seasonal distribution, with higher incidence in spring and winter. CONCLUSION: This is the first Italian study performed through the use of administrative data. Figures are in line but slightly higher than those published in other European countries.
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