S Prot-Labarthe1, T Weil2, N P K Nguyen2, A Berthe-Aucejo2, F Angoulvant3, R Boulkedid4, C Alberti5, O Bourdon6. 1. Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Inserm ECEVE unité 1123, 75019 Paris, France; Groupe pédiatrie de la Société française de pharmacie clinique, France. Electronic address: sonia.prot-labarthe@aphp.fr. 2. Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France. 3. Service d'accueil des urgences, hôpital Necker, AP-HP, 75015 Paris, France. 4. Unité d'épidémiologie clinique, hôpital Robert-Debré, AP-HP, 75019 Paris, France. 5. Inserm ECEVE unité 1123, 75019 Paris, France; Unité d'épidémiologie clinique, hôpital Robert-Debré, AP-HP, 75019 Paris, France. 6. Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Groupe pédiatrie de la Société française de pharmacie clinique, France; Pharmacie clinique, université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France; EA3412, laboratoire éducations et pratiques de santé, université Paris XIII, 93017 Bobigny, France.
Abstract
OBJECTIVE: Medication errors including inappropriate prescriptions and drug omissions are one of the causes of adverse drug events in children. Our aim was to develop a preliminary screening tool to detect omissions and inappropriate prescriptions in pediatrics based on French and international guidelines. MATERIEL AND METHODS: Disease classification was based on the prevalence rate of pathology and hospital statistics. The criteria were obtained by reviewing many French and international references. The Delphi consensus technique was used to establish the content validity of POPI. The level of agreement and the proposals of healthcare professionals was noted on a nine-point Likert scale. RESULTS: The criteria were categorized according to the main physiological systems (gastroenterology, respiratory infections, pain, neurology, dermatology, and miscellaneous). They were distributed to 16 French pediatric panelists (eight pharmacists, eight pediatricians who were hospital-based [50%] or working in the community [50%]). After two rounds of the Delphi process, 101 of 108 criteria were chosen with strong consensus (76 inappropriate prescriptions and 25 omissions). CONCLUSIONS: POPI is the first screening tool to detect inappropriate prescriptions and omissions in pediatrics. It is now necessary to conduct a prospective study to determine inter-rater reliability and the tool's detection capacity.
OBJECTIVE: Medication errors including inappropriate prescriptions and drug omissions are one of the causes of adverse drug events in children. Our aim was to develop a preliminary screening tool to detect omissions and inappropriate prescriptions in pediatrics based on French and international guidelines. MATERIEL AND METHODS: Disease classification was based on the prevalence rate of pathology and hospital statistics. The criteria were obtained by reviewing many French and international references. The Delphi consensus technique was used to establish the content validity of POPI. The level of agreement and the proposals of healthcare professionals was noted on a nine-point Likert scale. RESULTS: The criteria were categorized according to the main physiological systems (gastroenterology, respiratory infections, pain, neurology, dermatology, and miscellaneous). They were distributed to 16 French pediatric panelists (eight pharmacists, eight pediatricians who were hospital-based [50%] or working in the community [50%]). After two rounds of the Delphi process, 101 of 108 criteria were chosen with strong consensus (76 inappropriate prescriptions and 25 omissions). CONCLUSIONS: POPI is the first screening tool to detect inappropriate prescriptions and omissions in pediatrics. It is now necessary to conduct a prospective study to determine inter-rater reliability and the tool's detection capacity.
Authors: Aline de Oliveira Meireles Pires; Maria Beatriz Guimarães Ferreira; Kleiton Gonçalves do Nascimento; Márcia Marques Dos Santos Felix; Patrícia da Silva Pires; Maria Helena Barbosa Journal: Rev Lat Am Enfermagem Date: 2017-08-03