Mariana G Figueiro1, Claudia M Hunter1, Patricia Higgins2, Thomas Hornick3, Geoffrey E Jones1, Barbara Plitnick1, Jennifer Brons1, Mark S Rea1. 1. Lighting Research Center, Rensselaer Polytechnic Institute, Troy, NY, USA. 2. School of Nursing, Case Western Reserve University, Cleveland, OH, USA; School of Medicine, Case Western Reserve University, Cleveland, OH, USA. 3. School of Medicine, Case Western Reserve University, Cleveland, OH, USA; Geriatric Research Education and Clinical Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA.
Abstract
OBJECTIVES:Light therapy has shown promise as a nonpharmacological treatment to help regulate abnormal sleep-wake patterns and associated behavioral issues prevalent among individuals diagnosed with Alzheimer's disease and related dementia (ADRD). The present study investigated the effectiveness of a lighting intervention designed to increase circadian stimulation during the day using light sources that have high short-wavelength content and high light output. METHODS:Thirty-five persons with ADRD and 34 caregivers completed the 11-week study. During week 1, subjective questionnaires were administered to the study participants. During week 2, baseline data were collected using Daysimeters and actigraphs. Researchers installed the lighting during week 3, followed by 4 weeks of the tailored lighting intervention. During the last week of the lighting intervention, Daysimeter, actigraph and questionnaire data were again collected. Three weeks after the lighting intervention was removed, a third data collection (post-intervention assessment) was performed. RESULTS: The lighting intervention significantly increased circadian entrainment, as measured by phasor magnitude and sleep efficiency, as measured by actigraphy data, and significantly reduced symptoms of depression in the participants with ADRD. The caregivers also exhibited an increase in circadian entrainment during the lighting intervention; a seasonal effect of greater sleep efficiency and longer sleep duration was also found for caregivers. CONCLUSIONS: An ambient lighting intervention designed to increase daytime circadian stimulation can be used to increase sleep efficiency in persons with ADRD and their caregivers, and may also be effective for other populations such as healthy older adults with sleep problems, adolescents, and veterans with traumatic brain injury.
RCT Entities:
OBJECTIVES: Light therapy has shown promise as a nonpharmacological treatment to help regulate abnormal sleep-wake patterns and associated behavioral issues prevalent among individuals diagnosed with Alzheimer's disease and related dementia (ADRD). The present study investigated the effectiveness of a lighting intervention designed to increase circadian stimulation during the day using light sources that have high short-wavelength content and high light output. METHODS: Thirty-five persons with ADRD and 34 caregivers completed the 11-week study. During week 1, subjective questionnaires were administered to the study participants. During week 2, baseline data were collected using Daysimeters and actigraphs. Researchers installed the lighting during week 3, followed by 4 weeks of the tailored lighting intervention. During the last week of the lighting intervention, Daysimeter, actigraph and questionnaire data were again collected. Three weeks after the lighting intervention was removed, a third data collection (post-intervention assessment) was performed. RESULTS: The lighting intervention significantly increased circadian entrainment, as measured by phasor magnitude and sleep efficiency, as measured by actigraphy data, and significantly reduced symptoms of depression in the participants with ADRD. The caregivers also exhibited an increase in circadian entrainment during the lighting intervention; a seasonal effect of greater sleep efficiency and longer sleep duration was also found for caregivers. CONCLUSIONS: An ambient lighting intervention designed to increase daytime circadian stimulation can be used to increase sleep efficiency in persons with ADRD and their caregivers, and may also be effective for other populations such as healthy older adults with sleep problems, adolescents, and veterans with traumatic brain injury.
Authors: Diana Taibi Buchanan; Kevin Cain; Margaret Heitkemper; Robert Burr; Michael V Vitiello; Jasmine Zia; Monica Jarrett Journal: J Clin Sleep Med Date: 2014-09-15 Impact factor: 4.062
Authors: A Satlin; M H Teicher; H R Lieberman; R J Baldessarini; L Volicer; Y Rheaume Journal: Neuropsychopharmacology Date: 1991-09 Impact factor: 7.853
Authors: Mariana G Figueiro; Barbara Plitnick; Charles Roohan; Levent Sahin; Michael Kalsher; Mark S Rea Journal: J Clin Sleep Med Date: 2019-11-08 Impact factor: 4.062
Authors: Mariana G Figueiro; Philip D Sloane; Kimberly Ward; David Reed; Sheryl Zimmerman; John S Preisser; Seema Garg; Christopher J Wretman Journal: Behav Sleep Med Date: 2018-12-27 Impact factor: 2.964
Authors: Yeonsu Song; Raeanne C Moore; Dilip V Jeste; Mary-Lynn Brecht; Sonia Ancoli-Israel; Brent T Mausbach; Igor Grant Journal: J Clin Sleep Med Date: 2022-08-01 Impact factor: 4.324
Authors: Ivy C Mason; Mohamed Boubekri; Mariana G Figueiro; Brant P Hasler; Samer Hattar; Steven M Hill; Randy J Nelson; Katherine M Sharkey; Kenneth P Wright; Windy A Boyd; Marishka K Brown; Aaron D Laposky; Michael J Twery; Phyllis C Zee Journal: J Biol Rhythms Date: 2018-07-23 Impact factor: 3.182
Authors: Yeonsu Song; Susan M McCurry; Diane Lee; Karen R Josephson; Sarah Kate McGowan; Constance H Fung; Michael R Irwin; Edmond Teng; Cathy A Alessi; Jennifer L Martin Journal: Disabil Rehabil Date: 2019-10-26 Impact factor: 2.439