Literature DB >> 27065683

Gastrointestinal Stromal Tumor Mimicking as Ovarian Tumor in Gynaecologic Oncology.

Santosh K Ijeri1, Praveen S Rathod1, Rajshekar Kundargi1, V R Pallavi1, K Shobha1, C R Vijay2, K Uma Devi1, Uttam D Bafna1.   

Abstract

To report the clinical presentation and outcomes of a series of patients who presented with abdominal/pelvic mass or pelvic pain and were diagnosed with a gastrointestinal stromal tumor (GIST). Retrospective data were collected of all patients who presented with an abdominal/pelvic mass or pelvic pain between January 2010 and July 2015 and who were ultimately diagnosed with a GIST. The patients' medical records were reviewed. A literature review was also conducted. The event free survival and overall survival was calculated for all patients using Kaplan Meier curve (SPSS19-SPSS Inc. USA). A total ten patients were identified with GIST during the study period. Eight of ten patients had a tumor in the small intestine, one in sigmoid colon and one in base of small bowel mesentry. The mean tumor size was 13.9 cm (range, 3.9 to 24 cm). A complete resection was achieved in all 10 patients. No patient had distance metastasis. There were no intraoperative complications. One patient developed postoperative intestinal fistula and was managed conservatively. All patients were treated with imatinib after surgery. The mean follow-up time was 18 months (range, 2 to 47 months). The seven of the 10 patients (70 %) with no evidence of disease, two (20 %) lost follow up and one patient developed recurrence during follow up period and was started on sunitinib and patient died during follow up period because of disease. Gastrointestinal stromal tumors should be considered in the differential diagnosis of patients presenting with an abdominal/pelvic mass or pelvic pain in Gynaecologic oncology department. In such unusual circumstances the complete resection and appropriate adjuvant treatment results in complete durable remission.

Entities:  

Keywords:  Adnexal mass; Gastrointestinal stromal tumor; Incidental finding; Ovarian tumor

Year:  2015        PMID: 27065683      PMCID: PMC4811806          DOI: 10.1007/s13193-015-0479-8

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  26 in total

Review 1.  New developments in gastrointestinal stromal tumor.

Authors:  Jonathan C Trent; Robert S Benjamin
Journal:  Curr Opin Oncol       Date:  2006-07       Impact factor: 3.645

2.  Unusually large extraintestinal GIST presenting as an abdomino-pelvic tumor.

Authors:  Diana Matteo; Vani Dandolu; Larissa Lembert; Rebecca M Thomas; Ashwin J Chatwani
Journal:  Arch Gynecol Obstet       Date:  2007-12-08       Impact factor: 2.344

3.  Prognostic factors for primary GIST: prime time for personalized therapy?

Authors:  Chandrajit P Raut; Ronald P DeMatteo
Journal:  Ann Surg Oncol       Date:  2007-10-12       Impact factor: 5.344

Review 4.  Gastrointestinal stromal tumors: molecular markers and genetic subtypes.

Authors:  Christine M Barnett; Christopher L Corless; Michael C Heinrich
Journal:  Hematol Oncol Clin North Am       Date:  2013-08-26       Impact factor: 3.722

5.  Gastrointestinal stromal tumor presenting as a pelvic mass.

Authors:  Israel Zighelboim; Gwendolyn Henao; Anand Kunda; Carolina Gutierrez; Creighton Edwards
Journal:  Gynecol Oncol       Date:  2003-12       Impact factor: 5.482

6.  Surgically managed gastrointestinal stromal tumors: a comparative and prognostic analysis.

Authors:  Imran Hassan; Y Nancy You; Roman Shyyan; Eric J Dozois; Thomas C Smyrk; Scott H Okuno; Cathy D Schleck; David O Hodge; John H Donohue
Journal:  Ann Surg Oncol       Date:  2007-11-14       Impact factor: 5.344

Review 7.  Diagnosis of gastrointestinal stromal tumors: A consensus approach.

Authors:  Christopher D M Fletcher; Jules J Berman; Christopher Corless; Fred Gorstein; Jerzy Lasota; B Jack Longley; Markku Miettinen; Timothy J O'Leary; Helen Remotti; Brian P Rubin; Barry Shmookler; Leslie H Sobin; Sharon W Weiss
Journal:  Hum Pathol       Date:  2002-05       Impact factor: 3.466

8.  Anorectal gastrointestinal stromal tumors: CT and MR imaging features with clinical and pathologic correlation.

Authors:  Angela D Levy; Helen E Remotti; William M Thompson; Leslie H Sobin; Markku Miettinen
Journal:  AJR Am J Roentgenol       Date:  2003-06       Impact factor: 3.959

9.  Value of CT in the diagnosis and follow-up of gastrointestinal stromal tumors.

Authors:  Jing-Shan Gong; Min Zuo; Peng Yang; Da Zang; Yue Zhang; Ligang Xia; Jian-Min Xu; Xiaomei Wang; Xiaofang Yu
Journal:  Clin Imaging       Date:  2008 May-Jun       Impact factor: 1.605

10.  A gastrointestinal stromal tumor (GIST) masquerading as an ovarian mass.

Authors:  Giorgio Carlomagno; Pasquale Beneduce
Journal:  World J Surg Oncol       Date:  2004-05-13       Impact factor: 2.754

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  2 in total

1.  Gastrointestinal stromal tumor as mimicking gynecological mass finding on CT scan imaging: A case report.

Authors:  Devy Yuspita Rahma; Muhammad Hidayat Surya Atmaja
Journal:  Int J Surg Case Rep       Date:  2022-04-18

2.  Gastrointestinal Stromal Tumors Mimicking Gynecologic Disease: Clinicopathological Analysis of 20 Cases.

Authors:  Ying Liu; Maryam Shahi; Karin Miller; Christian F Meyer; Chien-Fu Hung; T-C Wu; Russell Vang; Deyin Xing
Journal:  Diagnostics (Basel)       Date:  2022-06-27
  2 in total

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