| Literature DB >> 27065579 |
Shreeniwas Raut1, Sandip Shah1, Kamalesh Shah1, Kinnari Patel1, Shailesh Talati1, Sonia Parikh1, Asha Anand1, Harsha Panchal1, Apurva Patel1, Akhil Jain1.
Abstract
We report analysis of all consecutive Hodgkins disease patients undergoing autologous hematopoietic stem cell transplant from September 1999 to December 2014. Out of total 38 patients 26 were males and 12 were females. 32 were adults and 6 were pediatric (<18 years). None were elderly. Median age was 28 years (9-61). All received BEAM protocol as conditioning regimen. Median engraftment time for granulocytes was 12 and 14 days for platelets. Thirty three (86.84 %) patients achieved complete remission out of which 8 (24.24 %) had further relapse. Transplant related mortality occurred in 4 (10 %) patients. Finally 26 (78.78 %) patients were disease free at median follow up of 60 months and median disease free survival (DFS) was 35 months. DFS was 66.66 and 65 %, respectively on 3 and 5 years. While overall survival was 70.83 and 70 % on 3 and 5 years, respectively.Entities:
Keywords: Autologus; Hodgkins; Stem cell; Transplantation
Year: 2015 PMID： 27065579 PMCID： PMC4789010 DOI： 10.1007/s12288-015-0559-5
Source DB: PubMed Journal: Indian J Hematol Blood Transfus ISSN： 0971-4502 Impact factor: 0.900