Literature DB >> 27062709

Adrenergic signaling in heart failure and cardiovascular aging.

Gaetano Santulli1, Guido Iaccarino2.   

Abstract

Both cardiovascular disease and aging are associated with changes in the sympathetic nervous system. Indeed, mounting evidence indicates that adrenergic receptors are functionally involved in numerous processes underlying both aging and cardiovascular disorders, in particular heart failure. This article will review the pathophysiological role of the sympathetic nervous system in heart failure and cardiovascular aging.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Aging; Beta adrenergic receptors; Cardiovascular system; G protein-coupled receptor kinases; Heart failure; Multimorbidity; Sympathetic nervous system

Mesh:

Substances:

Year:  2016        PMID: 27062709      PMCID: PMC5036981          DOI: 10.1016/j.maturitas.2016.03.022

Source DB:  PubMed          Journal:  Maturitas        ISSN: 0378-5122            Impact factor:   4.342


  120 in total

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