Nermin Tanik1, Özlem Balbaloğlu2, Mehmet Ucar2, Umıt Sarp3, Tugay Atalay4, Asuman Çelikbilek1, Ayşe Yeşim Göçmen5, Levent Ertugrul Inan1. 1. Department of Neurology, Bozok University Medical School, Yozgat, Turkey. 2. Department of Physical Treatment and Rehabilitation, Bozok University Medical School, Yozgat, Turkey. 3. Department of Physical Medicine and Rehabilitation, Yozgat State Hospital, Yozgat, Turkey. 4. Department of Neurosurgery, Bozok University Medical School, Yozgat, Turkey. 5. Department of Biochemistry, Bozok University Medical School, Yozgat, Turkey.
Abstract
OBJECTIVE: Vitamin D deficiencies are associated with a variety of chronic diseases. The goal of the present study was to investigate the relationship between vitamin D levels and carpal tunnel syndrome (CTS). METHODS: This study included 90 patients with mild to moderate CTS and assessed their routine serum 25-hydroxyvitamin D levels. Additionally, the pain level of each subject was evaluated using the Visual Analogue Scale and the Douleur Neuropathique 4 Questionnaire (DN4). RESULTS: The severity levels of CTS were at a 75% mild level in the vitamin D deficiency group and a 47.1% mild level in the vitamin D normal group, with a significant difference between groups (p = 0.008). Correlation analyses revealed positive correlations between body mass index and DN4 scores (r = 0.499, p = 0.025) and between vitamin D levels and CTS severity (r = 0.364, p = 0.004) in the vitamin D deficiency group. CONCLUSIONS: The present findings demonstrated that CTS may be triggered by vitamin D deficiency, and that the severity of CTS was correlated with vitamin D levels in the deficiency group. Additionally, there was a correlation between weight gain and neuropathic pain intensity in CTS patients with vitamin D deficiency. The present findings indicate that vitamin D levels should be assessed in CTS patients.
OBJECTIVE:Vitamin D deficiencies are associated with a variety of chronic diseases. The goal of the present study was to investigate the relationship between vitamin D levels and carpal tunnel syndrome (CTS). METHODS: This study included 90 patients with mild to moderate CTS and assessed their routine serum 25-hydroxyvitamin D levels. Additionally, the pain level of each subject was evaluated using the Visual Analogue Scale and the Douleur Neuropathique 4 Questionnaire (DN4). RESULTS: The severity levels of CTS were at a 75% mild level in the vitamin D deficiency group and a 47.1% mild level in the vitamin D normal group, with a significant difference between groups (p = 0.008). Correlation analyses revealed positive correlations between body mass index and DN4 scores (r = 0.499, p = 0.025) and between vitamin D levels and CTS severity (r = 0.364, p = 0.004) in the vitamin D deficiency group. CONCLUSIONS: The present findings demonstrated that CTS may be triggered by vitamin D deficiency, and that the severity of CTS was correlated with vitamin D levels in the deficiency group. Additionally, there was a correlation between weight gain and neuropathic pain intensity in CTSpatients with vitamin D deficiency. The present findings indicate that vitamin D levels should be assessed in CTSpatients.