Literature DB >> 27060999

Update on therapeutic interventions for the management of achalasia.

Nishmi Gunasingam1, Adam Perczuk2, Michael Talbot3, Arthur Kaffes4, Payal Saxena4.   

Abstract

Achalasia is a primary esophageal motility disorder. It is the absence of peristalsis in the esophageal body and inability of the lower esophageal sphincter to relax, which characterizes this rare condition. Its features typically include dysphagia, regurgitation, chest pain, and weight loss. The ultimate goal in treating achalasia is to relieve the patient's symptoms, improve esophageal emptying, and prevent further dilatation of the esophagus. Current treatment modalities targeted at achalasia include pharmacological therapy, endoscopic therapy, and surgery. This review focuses on the current therapeutic options and explores the role of peroral endoscopic myotomy in the management armamentarium.
© 2016 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  POEM; achalasia; laparoscopic Heller myotomy; peroral endoscopic myotomy

Mesh:

Substances:

Year:  2016        PMID: 27060999     DOI: 10.1111/jgh.13408

Source DB:  PubMed          Journal:  J Gastroenterol Hepatol        ISSN: 0815-9319            Impact factor:   4.029


  4 in total

Review 1.  The Role of Botulinum Toxin Injections for Esophageal Motility Disorders.

Authors:  Jessica L Sterling; Ron Schey; Zubair Malik
Journal:  Curr Treat Options Gastroenterol       Date:  2018-12

2.  Achalasia Patients Are at Nutritional Risk Regardless of Presenting Weight Category.

Authors:  Carolyn Newberry; Ravy K Vajravelu; Octavia Pickett-Blakely; Gary Falk; Yu Xiao Yang; Kristle L Lynch
Journal:  Dig Dis Sci       Date:  2018-02-22       Impact factor: 3.199

3.  The treatment of achalasia patients with esophageal varices: an international study.

Authors:  M Pesce; C Magee; R H Holloway; C P Gyawali; S Roman; M Pioche; E Savarino; F Quader; G Sarnelli; S Sanagapalli; A J Bredenoord; R Sweis
Journal:  United European Gastroenterol J       Date:  2019-03-29       Impact factor: 4.623

4.  Morphologic Restoration After Peroral Endoscopic Myotomy in Sigmoid-type Achalasia.

Authors:  Hong Jin Yoon; Jeung Eun Lee; Da Hyun Jung; Jun Chul Park; Young Hoon Youn; Hyojin Park
Journal:  J Neurogastroenterol Motil       Date:  2020-01-30       Impact factor: 4.924

  4 in total

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