Literature DB >> 27060779

Population variation of HLA genes in rural communities in Brazil, the Quilombos from the Vale do Ribeira, São Paulo - Brazil.

Kelly Nunes1, Bruno Piovezan2, Margareth A Torres2, Gerlândia N Pontes2, Lilian Kimura1, Juliana E P Carnavalli1, Regina Célia Mingroni Netto1, Maria Elisa Moraes2, Diogo Meyer3.   

Abstract

In the present study, we characterized the allelic and haplotypic profile of the genes HLA-A, -B, -C and -DRB1 (PCR-SBT) in a population sample of 144 highly admixed individuals, coming from rural communities in Brazil (Quilombos from Vale do Ribeira, in the State of São Paulo). Furthermore, we identified three individuals with a new null allele in the HLA-C gene (HLA-C(∗)02:105N), associated with the haplotype HLA-A(∗)80: 01∼B(∗)18: 01:01G∼DRB1(∗) 07:01.
Copyright © 2016 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Brazilian population; HLA; HLA haplotypes; New allele

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Year:  2016        PMID: 27060779     DOI: 10.1016/j.humimm.2016.04.007

Source DB:  PubMed          Journal:  Hum Immunol        ISSN: 0198-8859            Impact factor:   2.850


  1 in total

1.  How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians.

Authors:  Kelly Nunes; Vitor R C Aguiar; Márcio Silva; Alexandre C Sena; Danielli C M de Oliveira; Carla L Dinardo; Fernanda S G Kehdy; Eduardo Tarazona-Santos; Vanderson G Rocha; Anna Barbara F Carneiro-Proietti; Paula Loureiro; Miriam V Flor-Park; Claudia Maximo; Shannon Kelly; Brian Custer; Bruce S Weir; Ester C Sabino; Luís Cristóvão Porto; Diogo Meyer
Journal:  Front Immunol       Date:  2020-11-06       Impact factor: 7.561

  1 in total

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