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Literature DB >> 27060695

A Janus Mucoadhesive and Omniphobic Device for Gastrointestinal Retention.

Young-Ah Lucy Lee¹, Shiyi Zhang¹, Jiaqi Lin¹, Robert Langer^1,2, Giovanni Traverso^1,3.

Abstract

A novel Janus device with omniphobic and mucoadhesive sides that exhibit the unique capacity for antifouling and extended gastrointestinal retention is fabricated. This system enables repulsion of the food and fluid stream by the luminal-facing omniphobic side and allows attachment to the gastrointestinal mucosa by the mucoadhesive side.

Entities: Chemical Disease Species

Keywords: bioinspired; gastrointestinal retention; janus; mucoadhesive; omniphobic

Mesh：

Substances：
Adhesives
Water

Year: 2016 PMID： 27060695 PMCID： PMC5283723 DOI： 10.1002/adhm.201501036

Source DB: PubMed Journal: Adv Healthc Mater ISSN： 2192-2640 Impact factor: 9.933

36 in total

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Review 3. Janus colloidal particles: preparation, properties, and biomedical applications.

Authors: Chariya Kaewsaneha; Pramuan Tangboriboonrat; Duangporn Polpanich; Mohamed Eissa; Abdelhamid Elaissari
Journal: ACS Appl Mater Interfaces Date: 2013-03-07 Impact factor: 9.229

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Authors: Andreas Walther; Axel H E Müller
Journal: Chem Rev Date: 2013-04-04 Impact factor: 60.622

5. Surface forces and protein adsorption on dextran- and polyethylene glycol-modified polydimethylsiloxane.

Authors: Megan Farrell; Stephen Beaudoin
Journal: Colloids Surf B Biointerfaces Date: 2010-08-06 Impact factor: 5.268

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Authors: Hariharasudhan D Chirra; Tejal A Desai
Journal: Small Date: 2012-09-07 Impact factor: 13.281

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Authors: Nico Holmstock; Tom De Bruyn; Jan Bevernage; Pieter Annaert; Raf Mols; Jan Tack; Patrick Augustijns
Journal: Eur J Pharm Sci Date: 2013-02-09 Impact factor: 4.384

Review 8. Microfabricated implants for applications in therapeutic delivery, tissue engineering, and biosensing.

Authors: Kristy M Ainslie; Tejal A Desai
Journal: Lab Chip Date: 2008-09-19 Impact factor: 6.799

9. Bifunctional capsular dosage form: novel fanicular cylindrical gastroretentive system of clarithromycin and immediate release granules of ranitidine HCl for simultaneous delivery.

Authors: Pallavi Rajput; Deshvir Singh; Kamla Pathak
Journal: Int J Pharm Date: 2013-12-03 Impact factor: 5.875

Review 10. Advances in mucoadhesion and mucoadhesive polymers.

Authors: Vitaliy V Khutoryanskiy
Journal: Macromol Biosci Date: 2010-12-27 Impact factor: 4.979

3 in total

1. Intestinal mucoadhesive devices for oral delivery of insulin.

Authors: Amrita Banerjee; JooHee Lee; Samir Mitragotri
Journal: Bioeng Transl Med Date: 2016-08-19

2. Dynamic omnidirectional adhesive microneedle system for oral macromolecular drug delivery.

Authors: Wei Chen; Jacob Wainer; Si Won Ryoo; Xiaoyue Qi; Rong Chang; Jason Li; Seung Ho Lee; Seokkee Min; Adam Wentworth; Joy E Collins; Siddartha Tamang; Keiko Ishida; Alison Hayward; Robert Langer; Giovanni Traverso
Journal: Sci Adv Date: 2022-01-05 Impact factor: 14.136

Review 3. Mucosa-interfacing electronics.

Authors: Kewang Nan; Vivian R Feig; Binbin Ying; Julia G Howarth; Ziliang Kang; Yiyuan Yang; Giovanni Traverso
Journal: Nat Rev Mater Date: 2022-09-14 Impact factor: 76.679

3 in total