Roberto Rossini1, Daniela Monsellato2, Luca Bertolaccini2, Anna Pesci3, Giuseppe Zamboni3, Marcello Ceccaroni4, Giacomo Ruffo2. 1. Department of General Surgery, Sacro Cuore Hospital, Negrar, Verona, Italy. Electronic address: roberto.rossini@sacrocuore.it. 2. Department of General Surgery, Sacro Cuore Hospital, Negrar, Verona, Italy. 3. Department of Pathology, Sacro Cuore Hospital, Negrar, Verona, Italy. 4. Department of Gynecology, Sacro Cuore Hospital, Negrar, Verona, Italy.
Abstract
STUDY OBJECTIVE: To review our data for any correlation between the severity of endometriosis and lymph node involvement. DESIGN: Observational study with control (Canadian Task Force classification III). SETTING: Public medical center. PATIENTS: All women who underwent laparoscopic segmental rectal resection for endometriosis at our institution (Sacro Cuore Negrar Hospital) between 2000 and 2010. INTERVENTIONS: We retrospectively included 140 cases of colorectal surgery for intestinal endometriosis performed between 2004 and 2010 in our institution. Based on histopathological analysis of specimens, we divided our population into 2 groups: 70 patients with lymph node involvement and 70 patients without lymph node involvement. MEASUREMENTS AND MAIN RESULTS: No statistical correlation was found between the positivity of lymph nodes and the rate of intestinal stenosis, the histopathological specimen infiltration rate and depth and the intestinal recurrence rate. Only a poor correlation was found with preoperative CA-125 serous levels. CONCLUSION: The presence of lymph nodes involvement in intestinal resection specimens does not modify the natural history of the disease. The reason of its presence still has to be determined.
STUDY OBJECTIVE: To review our data for any correlation between the severity of endometriosis and lymph node involvement. DESIGN: Observational study with control (Canadian Task Force classification III). SETTING: Public medical center. PATIENTS: All women who underwent laparoscopic segmental rectal resection for endometriosis at our institution (Sacro Cuore Negrar Hospital) between 2000 and 2010. INTERVENTIONS: We retrospectively included 140 cases of colorectal surgery for intestinal endometriosis performed between 2004 and 2010 in our institution. Based on histopathological analysis of specimens, we divided our population into 2 groups: 70 patients with lymph node involvement and 70 patients without lymph node involvement. MEASUREMENTS AND MAIN RESULTS: No statistical correlation was found between the positivity of lymph nodes and the rate of intestinal stenosis, the histopathological specimen infiltration rate and depth and the intestinal recurrence rate. Only a poor correlation was found with preoperative CA-125 serous levels. CONCLUSION: The presence of lymph nodes involvement in intestinal resection specimens does not modify the natural history of the disease. The reason of its presence still has to be determined.