Literature DB >> 2706007

Studies on the inhibition of mitochondrial DNA replication by 3'-azido-3'-deoxythymidine and other dideoxynucleoside analogs which inhibit HIV-1 replication.

M V Simpson1, C D Chin, S A Keilbaugh, T S Lin, W H Prusoff.   

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Year:  1989        PMID: 2706007     DOI: 10.1016/0006-2952(89)90245-1

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  33 in total

1.  Ultrastructural changes associated with reduced mitochondrial DNA and impaired mitochondrial function in the presence of 2'3'-dideoxycytidine.

Authors:  L D Lewis; F M Hamzeh; P S Lietman
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

2.  Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity.

Authors:  Edward E McKee; Alice T Bentley; Matthew Hatch; Joel Gingerich; Delia Susan-Resiga
Journal:  Cardiovasc Toxicol       Date:  2004       Impact factor: 3.231

3.  Highly active antiretroviral therapy drug combination induces oxidative stress and mitochondrial dysfunction in immortalized human blood-brain barrier endothelial cells.

Authors:  Kalyan Reddy Manda; Atrayee Banerjee; William A Banks; Nuran Ercal
Journal:  Free Radic Biol Med       Date:  2010-12-28       Impact factor: 7.376

4.  Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondria.

Authors:  Kathleen A McCann; David W Williams; Edward E McKee
Journal:  J Neurochem       Date:  2012-05-21       Impact factor: 5.372

5.  Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis.

Authors:  J L Martin; C E Brown; N Matthews-Davis; J E Reardon
Journal:  Antimicrob Agents Chemother       Date:  1994-12       Impact factor: 5.191

6.  A computational model of mitochondrial AZT metabolism.

Authors:  Patrick C Bradshaw; Jiaxin Li; David C Samuels
Journal:  Biochem J       Date:  2005-12-01       Impact factor: 3.857

7.  Mitochondrial biogenesis in the axons of vertebrate peripheral neurons.

Authors:  Mandana Amiri; Peter J Hollenbeck
Journal:  Dev Neurobiol       Date:  2008-09-15       Impact factor: 3.964

8.  Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy.

Authors:  T M Sinnwell; K Sivakumar; S Soueidan; C Jay; J A Frank; A C McLaughlin; M C Dalakas
Journal:  J Clin Invest       Date:  1995-07       Impact factor: 14.808

9.  Myopathy in vitamin E deficient rats: muscle fibre necrosis associated with disturbances of mitochondrial function.

Authors:  P K Thomas; J M Cooper; R H King; J M Workman; A H Schapira; M A Goss-Sampson; D P Muller
Journal:  J Anat       Date:  1993-12       Impact factor: 2.610

10.  3'-Azido-3'-deoxythymidine-induced reduction in the ability of uninfected CD4-expressing cells to participate in syncytium formation.

Authors:  R W Buckheit; J Germany-Decker; K Qualls-Goodwin; B J Bowdon; W M Shannon
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

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