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Literature DB >> 27059512

Glucocorticoid-Regulated Kinase: Linking Azotemia and Muscle Wasting in CKD.

Madhav C Menon¹, John Cijiang He².

Abstract

Entities: Disease

Keywords: Azotemia; CKD-induced myopathy; Glucocorticoid-related kinase-1; knockout mice

Mesh：

Substances：
Glucocorticoids

Year: 2016 PMID： 27059512 PMCID： PMC5004666 DOI： 10.1681/ASN.2016030284

Source DB: PubMed Journal: J Am Soc Nephrol ISSN： 1046-6673 Impact factor: 10.121

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References

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19 in total

1. SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport.

Authors: J Wang; P Barbry; A C Maiyar; D J Rozansky; A Bhargava; M Leong; G L Firestone; D Pearce
Journal: Am J Physiol Renal Physiol Date: 2001-02

2. Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study.

Authors: Noël J M Cano; Denis Fouque; Hubert Roth; Michel Aparicio; Raymond Azar; Bernard Canaud; Philippe Chauveau; Christian Combe; Maurice Laville; Xavier M Leverve
Journal: J Am Soc Nephrol Date: 2007-07-26 Impact factor: 10.121

Review 3. (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms.

Authors: Florian Lang; Christoph Böhmer; Monica Palmada; Guiscard Seebohm; Nathalie Strutz-Seebohm; Volker Vallon
Journal: Physiol Rev Date: 2006-10 Impact factor: 37.312

4. Hemodialysis stimulates muscle and whole body protein loss and alters substrate oxidation.

Authors: T Alp Ikizler; Lara B Pupim; John R Brouillette; Deanna K Levenhagen; Kali Farmer; Raymond M Hakim; Paul J Flakoll
Journal: Am J Physiol Endocrinol Metab Date: 2002-01 Impact factor: 4.310

5. Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

Authors: Dan Yang Huang; Krishna M Boini; Björn Friedrich; Marco Metzger; Lothar Just; Hartmut Osswald; Peer Wulff; Dietmar Kuhl; Volker Vallon; Florian Lang
Journal: Am J Physiol Regul Integr Comp Physiol Date: 2005-11-10 Impact factor: 3.619

Glucocorticoid-Regulated Kinase: Linking Azotemia and Muscle Wasting in CKD.

1. SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport.

2. Intradialytic parenteral nutrition does not improve survival in malnourished hemodialysis patients: a 2-year multicenter, prospective, randomized study.

Review 3. (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms.

4. Hemodialysis stimulates muscle and whole body protein loss and alters substrate oxidation.

5. Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

Review 6. Inflammation and cachexia in chronic kidney disease.

7. Reduced synthesis of muscle proteins in chronic renal failure.

Review 8. Skeletal muscle development and regeneration.

9. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization.

10. Increased workload fully activates the blunted IRS-1/PI3-kinase/Akt signaling pathway in atrophied uremic muscle.