Literature DB >> 27057471

Disruption of evasive immune cell microenvironment in tumors reflects immunity induced by radiation therapy.

Alexander Filatenkov1, Jeanette Baker2, Samuel Strober1.   

Abstract

Radiation administered to murine colon tumors induced durable remissions that were dependent on CD4+ and CD8+ T cell immunity, and antigen cross priming CD8+ dendritic cells (DCs). Remissions were associated with marked reductions in the infiltration of myeloid-derived suppressor cells (MDSCs), tumor-associated macrophages (TAMs) and Treg cells, and a marked increase in CD8+ T cells.

Entities:  

Keywords:  tumor immunity; CD8 T cells; colon tumors; radiation therapy; tumor microenvironment

Year:  2016        PMID： 27057471      PMCID： PMC4801442          DOI： 10.1080/2162402X.2015.1072673

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  10 in total

1.  Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions.

Authors:  Alexander Filatenkov; Jeanette Baker; Antonia M S Mueller; Justin Kenkel; G-One Ahn; Suparna Dutt; Nigel Zhang; Holbrook Kohrt; Kent Jensen; Sussan Dejbakhsh-Jones; Judith A Shizuru; Robert N Negrin; Edgar G Engleman; Samuel Strober
Journal:  Clin Cancer Res       Date:  2015-04-13       Impact factor: 12.531

Review 2.  The role of stroma in immune recognition and destruction of well-established solid tumors.

Authors:  Ping Yu; Donald A Rowley; Yang-Xin Fu; Hans Schreiber
Journal:  Curr Opin Immunol       Date:  2006-02-03       Impact factor: 7.486

Review 3.  Immunosuppressive strategies that are mediated by tumor cells.

Authors:  Gabriel A Rabinovich; Dmitry Gabrilovich; Eduardo M Sotomayor
Journal:  Annu Rev Immunol       Date:  2007       Impact factor: 28.527

4.  Prevalence of FOXP3+ regulatory T cells increases during the progression of pancreatic ductal adenocarcinoma and its premalignant lesions.

Authors:  Nobuyoshi Hiraoka; Kaoru Onozato; Tomoo Kosuge; Setsuo Hirohashi
Journal:  Clin Cancer Res       Date:  2006-09-15       Impact factor: 12.531

Review 5.  Naturally arising CD25+CD4+ regulatory T cells in tumor immunity.

Authors:  T Nomura; S Sakaguchi
Journal:  Curr Top Microbiol Immunol       Date:  2005       Impact factor: 4.291

6.  CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.

Authors:  Y Naito; K Saito; K Shiiba; A Ohuchi; K Saigenji; H Nagura; H Ohtani
Journal:  Cancer Res       Date:  1998-08-15       Impact factor: 12.701

Review 7.  The role of NKT cells in tumor immunity.

Authors:  Masaki Terabe; Jay A Berzofsky
Journal:  Adv Cancer Res       Date:  2008       Impact factor: 6.242

8.  Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity.

Authors:  Kaori Sakuishi; Lionel Apetoh; Jenna M Sullivan; Bruce R Blazar; Vijay K Kuchroo; Ana C Anderson
Journal:  J Exp Med       Date:  2010-09-06       Impact factor: 14.307

Review 9.  Immunogenic cell death in cancer therapy.

Authors:  Guido Kroemer; Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel
Journal:  Annu Rev Immunol       Date:  2012-11-12       Impact factor: 28.527

10.  Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy.

Authors:  Helen Y Wang; Dean A Lee; Guangyong Peng; Zhong Guo; Yanchun Li; Yukiko Kiniwa; Ethan M Shevach; Rong Fu Wang
Journal:  Immunity       Date:  2004-01       Impact factor: 31.745
  10 in total
  2 in total

Review 1.  The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective.

Authors:  Robert H Press; Hui-Kuo G Shu; Hyunsuk Shim; James M Mountz; Brenda F Kurland; Richard L Wahl; Ella F Jones; Nola M Hylton; Elizabeth R Gerstner; Robert J Nordstrom; Lori Henderson; Karen A Kurdziel; Bhadrasain Vikram; Michael A Jacobs; Matthias Holdhoff; Edward Taylor; David A Jaffray; Lawrence H Schwartz; David A Mankoff; Paul E Kinahan; Hannah M Linden; Philippe Lambin; Thomas J Dilling; Daniel L Rubin; Lubomir Hadjiiski; John M Buatti
Journal:  Int J Radiat Oncol Biol Phys       Date:  2018-06-30       Impact factor: 7.038

Review 2.  Radiation-Induced Transformation of Immunoregulatory Networks in the Tumor Stroma.

Authors:  Inigo Martinez-Zubiaurre; Anthony J Chalmers; Turid Hellevik
Journal:  Front Immunol       Date:  2018-07-26       Impact factor: 7.561
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.