Literature DB >> 27055408

Non-functioning parathyroid adenoma: a rare differential diagnosis for vocal-cord paralysis.

D Kamali1, A Sharpe1, S Nagarajan1, W Elsaify1.   

Abstract

Introduction Adenomas of the parathyroid gland typically present with symptoms of hyperparathyroidism, manifested by fatigue, bone pain, abdominal pain, weakness, dyspepsia, nephrolithiasis and skeletal bone disease. Here, we describe, for the first time, a case of a non-functioning benign tumour of the parathyroid gland presenting as vocal-cord paralysis. Case History A 49-year-old male presented with a 10-week history of dysphonia and the feeling of having 'something stuck in my throat'. History-taking elicited no other associated symptoms. Flexible nasal endoscopy demonstrated paralysis of the left vocal cord. Computed tomography of the neck revealed a cystic lesion, 18mm in diameter adjacent to the oesophagus. After more rigorous tests, a neck exploration, left hemithyroidectomy, excision of the left paratracheal mass and level-VI neck dissection was undertaken, without incident to the patient or surgical team. Histology was consistent with a parathyroid adenoma. Conclusions This case emphasises the importance of including adenomatous disease of the parathyroid gland in the differential diagnosis despite normal parathyroid status as a cause of vocal cord palsy.

Entities:  

Keywords:  Hyperparathyroidism; Parathyroid adenoma; Vocal cord

Mesh:

Year:  2016        PMID: 27055408      PMCID: PMC5209966          DOI: 10.1308/rcsann.2016.0137

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  6 in total

1.  Parathyroid adenoma without hyperparathyroidism.

Authors:  Osamu Sekine; Yasuo Hozumi; Nobuyuki Takemoto; Hirokazu Kiyozaki; Shigeki Yamada; Fumio Konishi
Journal:  Jpn J Clin Oncol       Date:  2004-03       Impact factor: 3.019

2.  Parathyroid adenoma as a cause of vocal fold paralysis.

Authors:  Jih-Chin Lee; Gregory C Barkdull; Robert A Weisman
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2009-07

3.  Spontaneous vocal cord paresis and return to normocalcemia: an unusual presentation of parathyroid adenoma with concomitant abscess.

Authors:  P Angelos; N W Thompson; T J Giordano
Journal:  Surgery       Date:  1997-06       Impact factor: 3.982

4.  Sudden recurrent laryngeal nerve paralysis due to apoplexy of parathyroid adenoma.

Authors:  K Iwasaki; A Usami; I Oida; Y Hashimoto; H Morita; T Ozawa
Journal:  Auris Nasus Larynx       Date:  1999-01       Impact factor: 1.863

5.  Uncommon presentations of parathyroid adenoma.

Authors:  Daniel J Givens; Jason P Hunt; Brandon G Bentz
Journal:  Head Neck       Date:  2012-08-21       Impact factor: 3.147

6.  Diagnostic aspiration of parathyroid adenomas causes severe fibrosis complicating surgery and final histologic diagnosis.

Authors:  James Norman; Douglas Politz; Irwin Browarsky
Journal:  Thyroid       Date:  2007-12       Impact factor: 6.568

  6 in total
  2 in total

Review 1.  Selective venous sampling for primary hyperparathyroidism: how to perform an examination and interpret the results with reference to thyroid vein anatomy.

Authors:  Takayuki Yamada; Masaya Ikuno; Yasumoto Shinjo; Atsushi Hiroishi; Shoichiro Matsushita; Tsuyoshi Morimoto; Reiko Kumano; Kunihiro Yagihashi; Takuyuki Katabami
Journal:  Jpn J Radiol       Date:  2017-06-21       Impact factor: 2.374

2.  Sudden Odynophagia and Globus-A Unique Presentation of a Nonsecreting Parathyroid Adenoma: A Case Report and Literature Review.

Authors:  Luxman Srikantha; Esmael H Amjad; Rafic Beydoun
Journal:  Case Rep Otolaryngol       Date:  2020-12-29
  2 in total

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