Literature DB >> 27054976

Roche bets on bromodomains.

Eva von Schaper.   

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Year:  2016        PMID： 27054976     DOI： 10.1038/nbt0416-361

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  1 in total

1.  Tensha therapeutics.

Authors:  Jennifer Rohn
Journal:  Nat Biotechnol       Date:  2012-04-10       Impact factor: 54.908
  1 in total
  5 in total

Review 1.  Targeting Brd4 for cancer therapy: inhibitors and degraders.

Authors:  Yingchao Duan; Yuanyuan Guan; Wenping Qin; Xiaoyu Zhai; Bin Yu; Hongmin Liu
Journal:  Medchemcomm       Date:  2018-08-07       Impact factor: 3.597

Review 2.  Bromodomain and BET family proteins as epigenetic targets in cancer therapy: their degradation, present drugs, and possible PROTACs.

Authors:  Mohd Muddassir; Kunjal Soni; Chetan B Sangani; Abdullah Alarifi; Mohd Afzal; Naaser A Y Abduh; Yongtao Duan; Poonam Bhadja
Journal:  RSC Adv       Date:  2020-12-24       Impact factor: 4.036

3.  BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure.

Authors:  Qiming Duan; Sarah McMahon; Priti Anand; Hirsh Shah; Sean Thomas; Hazel T Salunga; Yu Huang; Rongli Zhang; Aarathi Sahadevan; Madeleine E Lemieux; Jonathan D Brown; Deepak Srivastava; James E Bradner; Timothy A McKinsey; Saptarsi M Haldar
Journal:  Sci Transl Med       Date:  2017-05-17       Impact factor: 17.956

4.  Elevated H3K27ac in aged skeletal muscle leads to increase in extracellular matrix and fibrogenic conversion of muscle satellite cells.

Authors:  Jiajian Zhou; Karl K So; Yuying Li; Yang Li; Jie Yuan; Yingzhe Ding; Fengyuan Chen; Yile Huang; Jin Liu; Wayne Lee; Gang Li; Zhenyu Ju; Hao Sun; Huating Wang
Journal:  Aging Cell       Date:  2019-07-20       Impact factor: 9.304

5.  Bromodomain and Extra-Terminal Inhibitor BMS-986158 Reverses Latent HIV-1 Infection In Vitro and Ex Vivo by Increasing CDK9 Phosphorylation and Recruitment.

Authors:  Xu-Sheng Huang; Ren-Rong Tian; Meng-Di Ma; Rong-Hua Luo; Liu-Meng Yang; Guang-Hui Peng; Mi Zhang; Xing-Qi Dong; Yong-Tang Zheng
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-10
  5 in total

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