Literature DB >> 27053734

Calcium, Reactive Oxygen Species, and Synaptic Plasticity.

Cecilia Hidalgo1, Alejandra Arias-Cavieres2.   

Abstract

In this review article, we address how activity-dependent Ca(2+)signaling is crucial for hippocampal synaptic/structural plasticity and discuss how changes in neuronal oxidative state affect Ca(2+)signaling and synaptic plasticity. We also analyze current evidence indicating that oxidative stress and abnormal Ca(2+)signaling contribute to age-related synaptic plasticity deterioration. ©2016 Int. Union Physiol. Sci./Am. Physiol. Soc.

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Year:  2016        PMID： 27053734     DOI： 10.1152/physiol.00038.2015

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


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