Literature DB >> 27053277

Prescription opioid use: Patient characteristics and misuse in community pharmacy.

Gerald Cochran, Jennifer L Bacci, Thomas Ylioja, Valerie Hruschak, Sharon Miller, Amy L Seybert, Ralph Tarter.   

Abstract

OBJECTIVES: Opioid pain medication misuse is a major concern for US public health. The purpose of this article is to: 1) describe the demographic and physical, behavioral, and mental health characteristics of patients who fill opioid medications in community pharmacy settings; and 2) describe the extent of opioid medication misuse behaviors among these patients.
DESIGN: We recruited and screened a convenience sample of patients with the use of a tablet computer-based assessment protocol that examined behavioral, mental, and physical health. Descriptive and inferential statistics were calculated to describe respondents and their opioid medication misuse and health characteristics.
SETTING: Patients were screened in 2 urban and 2 rural community pharmacies in southwestern Pennsylvania. PARTICIPANTS: Survey participants were adult patients filling opioid pain medications who were not currently receiving treatment for a cancer diagnosis. INTERVENTION: None. MAIN OUTCOME MEASURES: Validated screening measures included the Prescription Opioid Misuse Index, Alcohol Use Disorders Identification Test C, Short Form 12, Drug Abuse Screening Test 10, Primary Care Post-traumatic Stress Disorder (PTSD) screen, and the Patient Health Questionnaire 2.
RESULTS: A total of 333 patients were screened (71.2% response rate). Nearly the entire population reported pain above and general health below national norms. Hydrocodone (19.2%) and morphine (20.8%) were found to be the medications with the highest rates of misuse-with hydrocodone having more than 4 times higher odds of misuse compared with other medications (adjusted odds ratio [AOR] 4.48, 95% confidence interval [CI] 1.1-17.4). Patients with positive screens for illicit drug use (AOR 8.07, 95% CI 2.7-24.0), PTSD (AOR 5.88, 95% CI 2.3-14.7), and depression (AOR 2.44, 95% CI 1.0-5.9) also had significantly higher odds for misuse compared with those with negative screening results.
CONCLUSION: These findings provide important foundational data that suggest implementation of regular opioid misuse screening protocols within community pharmacies. Such screening activities could foster a culture of prevention and overall reduction for misuse among patients filling opioid medications in community pharmacies.
Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27053277      PMCID: PMC4886233          DOI: 10.1016/j.japh.2016.02.012

Source DB:  PubMed          Journal:  J Am Pharm Assoc (2003)        ISSN: 1086-5802


  47 in total

Review 1.  Nonmedical prescription opioid use and mental health and pain comorbidities: a narrative review.

Authors:  Erica Amari; Jürgen Rehm; Elliot Goldner; Benedikt Fischer
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2.  Validation of the Primary Care Posttraumatic Stress Disorder screening questionnaire (PC-PTSD) in civilian substance use disorder patients.

Authors:  Debora van Dam; Thomas Ehring; Ellen Vedel; Paul M G Emmelkamp
Journal:  J Subst Abuse Treat       Date:  2010-07-03

3.  An analysis of the root causes for opioid-related overdose deaths in the United States.

Authors:  Lynn R Webster; Susan Cochella; Nabarun Dasgupta; Keri L Fakata; Perry G Fine; Scott M Fishman; Todd Grey; Erin M Johnson; Lewis K Lee; Steven D Passik; John Peppin; Christina A Porucznik; Albert Ray; Sidney H Schnoll; Richard L Stieg; Wayne Wakeland
Journal:  Pain Med       Date:  2011-06       Impact factor: 3.750

4.  The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test.

Authors:  K Bush; D R Kivlahan; M B McDonell; S D Fihn; K A Bradley
Journal:  Arch Intern Med       Date:  1998-09-14

5.  Construct validity of the SF-12 in three different samples.

Authors:  Ulf Jakobsson; Albert Westergren; Susanne Lindskov; Peter Hagell
Journal:  J Eval Clin Pract       Date:  2011-01-06       Impact factor: 2.431

6.  Mechanisms of prescription drug diversion among drug-involved club- and street-based populations.

Authors:  James A Inciardi; Hilary L Surratt; Steven P Kurtz; Theodore J Cicero
Journal:  Pain Med       Date:  2007-03       Impact factor: 3.750

7.  Unintentional prescription opioid-related overdose deaths: description of decedents by next of kin or best contact, Utah, 2008-2009.

Authors:  Erin M Johnson; William A Lanier; Ray M Merrill; Jacob Crook; Christina A Porucznik; Robert T Rolfs; Brian Sauer
Journal:  J Gen Intern Med       Date:  2012-10-16       Impact factor: 5.128

Review 8.  Therapeutic opioids: a ten-year perspective on the complexities and complications of the escalating use, abuse, and nonmedical use of opioids.

Authors:  Laxmaiah Manchikanti; Angelie Singh
Journal:  Pain Physician       Date:  2008-03       Impact factor: 4.965

9.  Epidemiology of regular prescribed opioid use: results from a national, population-based survey.

Authors:  Teresa J Hudson; Mark J Edlund; Diane E Steffick; Shanti P Tripathi; Mark D Sullivan
Journal:  J Pain Symptom Manage       Date:  2008-07-10       Impact factor: 3.612

10.  Prescription Opioid Misuse Index: a brief questionnaire to assess misuse.

Authors:  Janet S Knisely; Martha J Wunsch; Karen L Cropsey; Eleanor D Campbell
Journal:  J Subst Abuse Treat       Date:  2008-07-26
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  15 in total

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Authors:  Christina Korownyk; Danielle Perry; Joey Ton; Michael R Kolber; Scott Garrison; Betsy Thomas; G Michael Allan; Cheryl Bateman; Raquel de Queiroz; Dorcas Kennedy; Wiplove Lamba; Jazmin Marlinga; Tally Mogus; Tony Nickonchuk; Eli Orrantia; Kim Reich; Nick Wong; Nicolas Dugré; Adrienne J Lindblad
Journal:  Can Fam Physician       Date:  2019-05       Impact factor: 3.275

2.  Managing opioid use disorder in primary care: PEER simplified guideline.

Authors:  Christina Korownyk; Danielle Perry; Joey Ton; Michael R Kolber; Scott Garrison; Betsy Thomas; G Michael Allan; Cheryl Bateman; Raquel de Queiroz; Dorcas Kennedy; Wiplove Lamba; Jazmin Marlinga; Tally Mogus; Tony Nickonchuk; Eli Orrantia; Kim Reich; Nick Wong; Nicolas Dugré; Adrienne J Lindblad
Journal:  Can Fam Physician       Date:  2019-05       Impact factor: 3.275

3.  Prescription Opioid Misuse Among Rural Community Pharmacy Patients: Pilot Study for Screening and Implications for Future Practice and Research.

Authors:  Gerald T Cochran; Rafael J Engel; Valerie J Hruschak; Ralph E Tarter
Journal:  J Pharm Pract       Date:  2016-07-08

4.  The opioid and related drug epidemics in rural Appalachia: A systematic review of populations affected, risk factors, and infectious diseases.

Authors:  Christine A Schalkoff; Kathryn E Lancaster; Bradley N Gaynes; Vivian Wang; Brian W Pence; William C Miller; Vivian F Go
Journal:  Subst Abus       Date:  2019-08-12       Impact factor: 3.716

5.  A community pharmacy-led intervention for opioid medication misuse: A small-scale randomized clinical trial.

Authors:  Gerald Cochran; Qi Chen; Craig Field; Amy L Seybert; Valerie Hruschak; Amanda Jaber; Adam J Gordon; Ralph Tarter
Journal:  Drug Alcohol Depend       Date:  2019-10-22       Impact factor: 4.492

6.  Alcohol, marijuana, and opioid use disorders: 5-Year patterns and characteristics of emergency department encounters.

Authors:  Amber L Bahorik; Derek D Satre; Andrea H Kline-Simon; Constance M Weisner; Kelly C Young-Wolff; Cynthia I Campbell
Journal:  Subst Abus       Date:  2017-09-06       Impact factor: 3.716

Review 7.  The Interaction Between Chronic Pain and PTSD.

Authors:  Shelley Kind; John D Otis
Journal:  Curr Pain Headache Rep       Date:  2019-11-28

8.  A community pharmacy intervention for opioid medication misuse: A pilot randomized clinical trial.

Authors:  Gerald Cochran; Craig Field; Jordan Karp; Amy L Seybert; Qi Chen; Whitney Ringwald; Valerie Hruschak; Sunita Chickering; Joelle Kincman; Amanda Jaber; Ralph Tarter
Journal:  J Am Pharm Assoc (2003)       Date:  2018 Jul - Aug

9.  Addressing the opioid crisis globally.

Authors:  Nora D Volkow; María Elena Medina-Mora Icaza; Vladimir Poznyak; Shekhar Saxena; Gilberto Gerra
Journal:  World Psychiatry       Date:  2019-06       Impact factor: 49.548

10.  Brief intervention medication therapy management: Establishment of an opioid misuse intervention model delivered in a community pharmacy.

Authors:  Amy Kenney; Nicholas Cox; M Aryana Bryan; Gerald Cochran
Journal:  Am J Health Syst Pharm       Date:  2021-02-08       Impact factor: 2.637

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