Isin Ureyen1, Ozgur Ozyuncu2, Nihal Sahin-Uysal3, Ozgur Kara4, Derman Basaran5, Mert Turgal2, Ozgur Deren2. 1. a Department of Gynecology and Obstetrics , Antalya Training and Research Hospital , Antalya , Turkey. 2. b Department of Gynecology and Obstetrics , Hacettepe University Medical School , Ankara , Turkey. 3. c Department of Gynecology and Obstetrics , Başkent University Medical School , Ankara , Turkey. 4. d Department of Gynecology and Obstetrics , Zekai Tahir Burak Women's Health Teaching and Research Hospital , Ankara , Turkey , and. 5. e Department of Gynecology and Obstetrics , Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital , Ankara , Turkey.
Abstract
OBJECTIVE: In this study, we investigated the relationship of mean platelet volume (MPV) with the presence and the severity of intrauterine growth restriction (IUGR) and with neonatal complications. METHODS: The pregnancies with and without IUGR, that were followed-up in our hospital between 2003 and 2009 were analyzed retrospectively. Pregnancies which resulted in birth of a newborn with a birthweight less than 10th percentile for the gestational age were selected for IUGR group. IUGR cases were divided into three groups according to the Doppler parameters. RESULTS: There was no significant difference between the MPV values in the groups. There was no association between MPV and Doppler parameters that can be used in predicting the severity of IUGR. There was no significant relation between MPV and the perinatal complications such as intracranial hemorrhage (ICH), bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), the development of sepsis, postpartum exitus (PPEX) and intrauterine exitus (IUEX). Higher MPV values were associated with hospitalization in the neonatal intensive care unit (NICU) and respiratory distress syndrome (RDS) in the IUGR group. CONCLUSION: Analysis of MPV is a simple and readily available laboratory test. Prospective researches employing standard measurement technics are required to clarify the relationship between MPV and IUGR.
OBJECTIVE: In this study, we investigated the relationship of mean platelet volume (MPV) with the presence and the severity of intrauterine growth restriction (IUGR) and with neonatal complications. METHODS: The pregnancies with and without IUGR, that were followed-up in our hospital between 2003 and 2009 were analyzed retrospectively. Pregnancies which resulted in birth of a newborn with a birthweight less than 10th percentile for the gestational age were selected for IUGR group. IUGR cases were divided into three groups according to the Doppler parameters. RESULTS: There was no significant difference between the MPV values in the groups. There was no association between MPV and Doppler parameters that can be used in predicting the severity of IUGR. There was no significant relation between MPV and the perinatal complications such as intracranial hemorrhage (ICH), bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), the development of sepsis, postpartum exitus (PPEX) and intrauterine exitus (IUEX). Higher MPV values were associated with hospitalization in the neonatal intensive care unit (NICU) and respiratory distress syndrome (RDS) in the IUGR group. CONCLUSION: Analysis of MPV is a simple and readily available laboratory test. Prospective researches employing standard measurement technics are required to clarify the relationship between MPV and IUGR.
Entities:
Keywords:
Intrauterine growth restriction; mean platelet volume; perinatal complications
Authors: Anca Marina Ciobanu; Anca Maria Panaitescu; Nicolae Gica; Ana Maria Scutelnicu; Alexandra Bouariu; Mihaela Roxana Popescu Journal: Medicina (Kaunas) Date: 2021-12-12 Impact factor: 2.430