| Literature DB >> 27051044 |
Patrick C Y Woo1, Susanna K P Lau2, Garnet K Y Choi3, Yi Huang3, Saritha Sivakumar4, Hoi-Wah Tsoi3, Cyril C Y Yip3, Shanty V Jose4, Ru Bai3, Emily Y M Wong3, Marina Joseph4, Tong Li3, Ulrich Wernery5, Kwok-Yung Yuen2.
Abstract
Previously, we reported the discovery of a novel canine picornavirus (CanPV) in the fecal sample of a dog. In this molecular epidemiology study, CanPV was detected in 15 (1.11%) of 1347 canine fecal samples from Hong Kong and one (0.76%) of 131 canine fecal samples from Dubai, with viral loads 1.06×10(3) to 6.64×10(6) copies/ml. Complete genome sequencing and phylogenetic analysis showed that CanPV was clustered with feline picornavirus (FePV), bat picornavirus (BatPV) 1 to 3, Ia io picornavirus 1 (IaioPV1) and bovine picornavirus (BoPV), and this cluster was most closely related to the genera Enterovirus and Sapelovirus. The Ka/Ks ratios of all the coding regions were <0.1. According to the definition of the Picornavirus Study Group of ICTV, CanPV, FePV, BatPV 1 to 3, IaioPV1 and BoPV should constitute a novel genus in Picornaviridae. BEAST analysis showed that this genus diverged from its most closely related genus, Sapelovirus, about 49 years ago.Entities:
Keywords: animal RNA viruses; dog; picornavirus
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Year: 2016 PMID： 27051044 DOI： 10.1016/j.meegid.2016.03.033
Source DB: PubMed Journal: Infect Genet Evol ISSN： 1567-1348 Impact factor: 3.342