Literature DB >> 27050975

Significance of TNF-α and IL-6 expression in invasive pituitary adenomas.

J L Wu1, J Y Qiao2, Q H Duan1.   

Abstract

The aim of this study was to investigate expression of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in invasive pituitary adenomas (IPAs). The streptavidin peroxidase immunohistochemical method was employed to detect their expression in 40 cases of IPA and 40 of non-invasive pituitary adenoma (NIPA). TNF-α and IL-6 were found to be upregulated in IPA tissue compared with that of NIPA (P < 0.05). These proteins may therefore play important roles in the occurrence and progression of IPA.

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Year:  2016        PMID: 27050975     DOI: 10.4238/gmr.15017502

Source DB:  PubMed          Journal:  Genet Mol Res        ISSN: 1676-5680


  2 in total

1.  Association of NM23 polymorphisms and clinicopathological features and recurrence of invasive pituitary adenomas.

Authors:  Hua Wang; Wenyuan Sang
Journal:  Pituitary       Date:  2020-04       Impact factor: 4.107

2.  Giant cabergoline-resistant prolactinoma in a man who presented with a psychotic episode during treatment: a case report.

Authors:  Luiz Augusto Casulari; Lucas Faria de Castro; Iruena Moraes Kessler; José Luiz Mendonça; Maria de Fátima Magalhães Gonzaga
Journal:  J Med Case Rep       Date:  2019-06-16
  2 in total

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