Literature DB >> 27050683

Exposing the Molecular Machinery of BK Polyomavirus.

Christopher B Buck1.   

Abstract

BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting this potentially deadly virus. The study also serves as a platform for exploring the basic biology of virion assembly and infectious entry.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID： 27050683      PMCID： PMC6289593          DOI： 10.1016/j.str.2016.03.011

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  7 in total

1.  Broadly neutralizing human monoclonal JC polyomavirus VP1-specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy.

Authors:  Ivan Jelcic; Benoit Combaluzier; Ilijas Jelcic; Wolfgang Faigle; Luzia Senn; Brenda J Reinhart; Luisa Ströh; Roger M Nitsch; Thilo Stehle; Mireia Sospedra; Jan Grimm; Roland Martin
Journal:  Sci Transl Med       Date:  2015-09-23       Impact factor: 17.956

2.  Commercially available immunoglobulins contain virus neutralizing antibodies against all major genotypes of polyomavirus BK.

Authors:  P Randhawa; D V Pastrana; G Zeng; Y Huang; R Shapiro; P Sood; C Puttarajappa; M Berger; S Hariharan; C B Buck
Journal:  Am J Transplant       Date:  2015-03-03       Impact factor: 8.086

3.  BK-virus and the impact of pre-emptive immunosuppression reduction: 5-year results.

Authors:  K L Hardinger; M J Koch; D J Bohl; G A Storch; D C Brennan
Journal:  Am J Transplant       Date:  2010-01-05       Impact factor: 8.086

4.  Identification of species-specific and cross-reactive epitopes in human polyomavirus capsids using monoclonal antibodies.

Authors:  Parmjeet Randhawa; Raphael Viscidi; Joseph J Carter; Denise A Galloway; Tim D Culp; Cathy Huang; Bala Ramaswami; Neil D Christensen
Journal:  J Gen Virol       Date:  2009-03       Impact factor: 3.891

Review 5.  Human polyomaviruses in disease and cancer.

Authors:  Tina Dalianis; Hans H Hirsch
Journal:  Virology       Date:  2013-01-26       Impact factor: 3.616

6.  BK polyomavirus genotypes represent distinct serotypes with distinct entry tropism.

Authors:  Diana V Pastrana; Upasana Ray; Thomas G Magaldi; Rachel M Schowalter; Nicolas Çuburu; Christopher B Buck
Journal:  J Virol       Date:  2013-07-10       Impact factor: 5.103

7.  Neutralization serotyping of BK polyomavirus infection in kidney transplant recipients.

Authors:  Diana V Pastrana; Daniel C Brennan; Nicolas Cuburu; Gregory A Storch; Raphael P Viscidi; Parmjeet S Randhawa; Christopher B Buck
Journal:  PLoS Pathog       Date:  2012-04-12       Impact factor: 6.823
  7 in total
  2 in total

1.  Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection.

Authors:  Margarita-Maria Panou; Emma L Prescott; Daniel L Hurdiss; Gemma Swinscoe; Michael Hollinshead; Laura G Caller; Ethan L Morgan; Louisa Carlisle; Marietta Müller; Michelle Antoni; David Kealy; Neil A Ranson; Colin M Crump; Andrew Macdonald
Journal:  Int J Mol Sci       Date:  2018-03-19       Impact factor: 5.923

2.  The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors.

Authors:  Daniel L Hurdiss; Martin Frank; Joseph S Snowden; Andrew Macdonald; Neil A Ranson
Journal:  Structure       Date:  2018-04-26       Impact factor: 5.006
  2 in total

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