| Literature DB >> 27050657 |
Hongxin Liu1, Ling Zhang1, Yuchan Chen1, Saini Li1, Guohui Tan1, Zhanghua Sun1, Qingling Pan1, Wei Ye1, Haohua Li1, Weimin Zhang1.
Abstract
Two new pimarane-type diterpenes, scopararanes H-I (1-2), along with five known ones (3-7) were isolated from the culture broth of a marine sediment-derived fungus Eutypella sp. FS46, which was obtained from the South China Sea. Their structures were established by extensive spectroscopic analysis. All of them were evaluated for their cytotoxic activities against MCF-7, NCI-H460 and SF-268 tumour cell lines. Scopararane I (2) showed moderate inhibitory activities.Entities:
Keywords: Eutypella sp. FS46; cytotoxic activity; pimarane diterpenes; scopararane H; scopararane I
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Year: 2016 PMID： 27050657 DOI： 10.1080/14786419.2016.1169418
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861