| Literature DB >> 27049559 |
Jung-Ick Byun1, Soon-Tae Lee1, Keun-Hwa Jung1, Jun-Sang Sunwoo1, Jangsup Moon2, Tae-Joon Kim1, Jung-Ah Lim1, Soyun Kim3, Do-Yong Kim3, Su-Hyun Han4, Hyemin Jang5, Hong Il Suh6, A-Hyun Cho7, Dong Wook Kim8, Jung-Won Shin9, Yong Seo Koo10, Woo Chan Choi11, Woong-Woo Lee12, Nari Choi13, Seongheon Kim14, Hyunwoo Nam15, Dae Lim Koo15, Minah Kim16, Byung Chan Lim17, Jong-Hee Chae17, Ki Joong Kim17, Daejong Jeon3, Kyung-Il Park18, Ki-Young Jung1, Manho Kim19, Kon Chu20, Sang Kun Lee21.
Abstract
We aimed to evaluate the prevalence of antineuronal antibodies in a nationwide cohort of patients with encephalopathy of unknown etiology. We screened 1699 patients with idiopathic encephalopathy who were referred from 70 hospitals across Korea for autoimmune synaptic and classic paraneoplastic antibodies. Those with cerebellar degeneration, sensory polyneuropathy or other paraneoplastic syndromes without encephalopathy were not included in this study. One-hundred and four patients (6.12%) had antibody-associated autoimmune encephalopathy. Autoimmune synaptic antibodies were identified in 89 patients (5.24%) and classic paraneoplastic antibodies were identified in 16 patients (0.94%). The patients with antibody-associated autoimmune encephalopathy comprised a small but significant portion of the total number of patients with encephalopathy of unknown cause.Entities:
Keywords: Autoimmune; Autoimmune synaptic antibody; Classic paraneoplastic antibody; Encephalopathy; Prevalence
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Year: 2016 PMID： 27049559 DOI： 10.1016/j.jneuroim.2016.02.002
Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478